Intracranial myeloid sarcoma as the first presentation of acute myeloid leukemia and literature review

© 2023. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature..

INTRODUCTION: Intracranial myeloid sarcoma is a rare extramedullary presentation of acute myeloid leukemia (AML). It can involve the meninges and ependyma presenting as extra-axial mass lesion. Rarely, it can also invade the brain parenchyma. It is commonly seen in children. It is usually misdiagnosed due to its close resemblance to other intracranial tumors (meningioma, metastasis, Ewing's sarcomas, and lymphoma). These are underdiagnosed if they precede the diagnosis of leukemia.

CASE REPORT: A 7-year-old boy with isolated intracranial myeloid sarcoma who presented with raised intracranial pressure (ICP) which was successfully managed by surgical excision.

CONCLUSION: Isolated intracranial myeloid sarcoma is a rare presentation of AML. Leukemia can be diagnosed early during the postoperative period and can be started on therapy timely. These patients requires regular follow-ups (clinical, laboratory and radiological) to detect relapses early.

Medienart:

E-Artikel

Erscheinungsjahr:

2023

Erschienen:

2023

Enthalten in:

Zur Gesamtaufnahme - volume:39

Enthalten in:

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery - 39(2023), 12 vom: 10. Dez., Seite 3607-3612

Sprache:

Englisch

Beteiligte Personen:

Kumarasamy, Sivaraman [VerfasserIn]
Garg, Kanwaljeet [VerfasserIn]
Sharma, M C [VerfasserIn]
Chandra, P S [VerfasserIn]

Links:

Volltext

Themen:

Acute myeloid leukemia
Case Reports
Extra-axial
Journal Article
Myeloid sarcoma
Raised ICP
Review

Anmerkungen:

Date Completed 29.11.2023

Date Revised 29.11.2023

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1007/s00381-023-06016-w

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM358023203