Projected Savings for Generic Oncology Drugs Purchased via Mark Cuban Cost Plus Drug Company Versus in Medicare
PURPOSE: Self-administered oncology drugs contribute disproportionately to Medicare Part D spending; prices often remain high even after generic entry. Outlets for low-cost drugs such as Mark Cuban Cost Plus Drug Company (MCCPDC) offer opportunities for decreased Medicare, Part D, and beneficiary spending. We estimate potential savings if Part D plans obtained prices such as those offered under the MCCPDC for seven generic oncology drugs.
METHODS: Using the 2020 Medicare Part D Spending dashboard, Q3-2022 Part D formulary prices, and Q3-2022 MCCPDC prices for seven self-administered generic oncology drugs, we estimated Medicare savings by replacing Q3-2022 Part D unit costs with costs under the MCCPDC plan.
RESULTS: We estimate potential savings of $661.8 million (M) US dollars (USD; 78.8%) for the seven oncology drugs studied. Total savings ranged from $228.1M USD (56.1%) to $2,154.5M USD (92.4%) compared with 25th and 75th percentiles of Part D plan unit prices. The median savings replacing Part D plan prices were abiraterone $338.0M USD, anastrozole $1.2M USD, imatinib 100 mg $15.6M USD, imatinib 400 mg $212.0M USD, letrozole $1.9M USD, methotrexate $26.7M USD, raloxifene $63.8M USD, and tamoxifen $2.6M USD. All 30-day prescription drug prices offered by MCCPDC generated cost savings except for three drugs offered at the 25th percentile Part D formulary pricing: anastrozole, letrozole, and tamoxifen.
CONCLUSION: Replacing current Part D median formulary prices with MCCPDC pricing could yield significant savings for seven generic oncology drugs. Individual beneficiaries could save nearly $25,200 USD per year for abiraterone or between $17,500 USD and $20,500 USD for imatinib. Notably, Part D cash-pay prices for abiraterone and imatinib under the catastrophic phase of coverage were still more expensive than baseline MCCPDC prices.
Medienart: |
E-Artikel |
---|
Erscheinungsjahr: |
2023 |
---|---|
Erschienen: |
2023 |
Enthalten in: |
Zur Gesamtaufnahme - volume:41 |
---|---|
Enthalten in: |
Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 41(2023), 29 vom: 10. Okt., Seite 4664-4668 |
Sprache: |
Englisch |
---|
Beteiligte Personen: |
Cortese, Brian D [VerfasserIn] |
---|
Links: |
---|
Themen: |
094ZI81Y45 |
---|
Anmerkungen: |
Date Completed 09.10.2023 Date Revised 18.10.2023 published: Print-Electronic Citation Status MEDLINE |
---|
doi: |
10.1200/JCO.23.00079 |
---|
funding: |
|
---|---|
Förderinstitution / Projekttitel: |
|
PPN (Katalog-ID): |
NLM357918339 |
---|
LEADER | 01000naa a22002652 4500 | ||
---|---|---|---|
001 | NLM357918339 | ||
003 | DE-627 | ||
005 | 20231226073630.0 | ||
007 | cr uuu---uuuuu | ||
008 | 231226s2023 xx |||||o 00| ||eng c | ||
024 | 7 | |a 10.1200/JCO.23.00079 |2 doi | |
028 | 5 | 2 | |a pubmed24n1193.xml |
035 | |a (DE-627)NLM357918339 | ||
035 | |a (NLM)37290029 | ||
040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
041 | |a eng | ||
100 | 1 | |a Cortese, Brian D |e verfasserin |4 aut | |
245 | 1 | 0 | |a Projected Savings for Generic Oncology Drugs Purchased via Mark Cuban Cost Plus Drug Company Versus in Medicare |
264 | 1 | |c 2023 | |
336 | |a Text |b txt |2 rdacontent | ||
337 | |a ƒaComputermedien |b c |2 rdamedia | ||
338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
500 | |a Date Completed 09.10.2023 | ||
500 | |a Date Revised 18.10.2023 | ||
500 | |a published: Print-Electronic | ||
500 | |a Citation Status MEDLINE | ||
520 | |a PURPOSE: Self-administered oncology drugs contribute disproportionately to Medicare Part D spending; prices often remain high even after generic entry. Outlets for low-cost drugs such as Mark Cuban Cost Plus Drug Company (MCCPDC) offer opportunities for decreased Medicare, Part D, and beneficiary spending. We estimate potential savings if Part D plans obtained prices such as those offered under the MCCPDC for seven generic oncology drugs | ||
520 | |a METHODS: Using the 2020 Medicare Part D Spending dashboard, Q3-2022 Part D formulary prices, and Q3-2022 MCCPDC prices for seven self-administered generic oncology drugs, we estimated Medicare savings by replacing Q3-2022 Part D unit costs with costs under the MCCPDC plan | ||
520 | |a RESULTS: We estimate potential savings of $661.8 million (M) US dollars (USD; 78.8%) for the seven oncology drugs studied. Total savings ranged from $228.1M USD (56.1%) to $2,154.5M USD (92.4%) compared with 25th and 75th percentiles of Part D plan unit prices. The median savings replacing Part D plan prices were abiraterone $338.0M USD, anastrozole $1.2M USD, imatinib 100 mg $15.6M USD, imatinib 400 mg $212.0M USD, letrozole $1.9M USD, methotrexate $26.7M USD, raloxifene $63.8M USD, and tamoxifen $2.6M USD. All 30-day prescription drug prices offered by MCCPDC generated cost savings except for three drugs offered at the 25th percentile Part D formulary pricing: anastrozole, letrozole, and tamoxifen | ||
520 | |a CONCLUSION: Replacing current Part D median formulary prices with MCCPDC pricing could yield significant savings for seven generic oncology drugs. Individual beneficiaries could save nearly $25,200 USD per year for abiraterone or between $17,500 USD and $20,500 USD for imatinib. Notably, Part D cash-pay prices for abiraterone and imatinib under the catastrophic phase of coverage were still more expensive than baseline MCCPDC prices | ||
650 | 4 | |a Journal Article | |
650 | 7 | |a Drugs, Generic |2 NLM | |
650 | 7 | |a Anastrozole |2 NLM | |
650 | 7 | |a 2Z07MYW1AZ |2 NLM | |
650 | 7 | |a Imatinib Mesylate |2 NLM | |
650 | 7 | |a 8A1O1M485B |2 NLM | |
650 | 7 | |a Letrozole |2 NLM | |
650 | 7 | |a 7LKK855W8I |2 NLM | |
650 | 7 | |a Prescription Drugs |2 NLM | |
650 | 7 | |a Tamoxifen |2 NLM | |
650 | 7 | |a 094ZI81Y45 |2 NLM | |
700 | 1 | |a Dusetzina, Stacie B |e verfasserin |4 aut | |
700 | 1 | |a Luckenbaugh, Amy N |e verfasserin |4 aut | |
700 | 1 | |a Al Hussein Al Awamlh, Bashir |e verfasserin |4 aut | |
700 | 1 | |a Stimson, C J |e verfasserin |4 aut | |
700 | 1 | |a Barocas, Daniel A |e verfasserin |4 aut | |
700 | 1 | |a Penson, David F |e verfasserin |4 aut | |
700 | 1 | |a Chang, Sam S |e verfasserin |4 aut | |
700 | 1 | |a Talwar, Ruchika |e verfasserin |4 aut | |
773 | 0 | 8 | |i Enthalten in |t Journal of clinical oncology : official journal of the American Society of Clinical Oncology |d 1986 |g 41(2023), 29 vom: 10. Okt., Seite 4664-4668 |w (DE-627)NLM012608777 |x 1527-7755 |7 nnns |
773 | 1 | 8 | |g volume:41 |g year:2023 |g number:29 |g day:10 |g month:10 |g pages:4664-4668 |
856 | 4 | 0 | |u http://dx.doi.org/10.1200/JCO.23.00079 |3 Volltext |
912 | |a GBV_USEFLAG_A | ||
912 | |a GBV_NLM | ||
951 | |a AR | ||
952 | |d 41 |j 2023 |e 29 |b 10 |c 10 |h 4664-4668 |