Primary Thymic Mucinous Adenocarcinoma with Extensive Punctate and Amorphous Calcifications : A Case Report

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BACKGROUND: Primary thymic mucinous adenocarcinoma is an extremely rare and aggressive tumor with poor prognosis. The tumor may present as aheterogeneous solid or cystic mass accompanied by calcifications. However, clinical and radiologic features of the tumor are not well known dueto the rarity of the disease, which makes accurate diagnosis difficult.

CASE PRESENTATION: Here we present a rare case of primary thymic mucinous adenocarcinoma in the anterior mediastinum, including computed tomography (CT) andmagnetic resonance imaging (MRI) findings. Chest computed tomography revealed a large anterior mediastinal mass with extensive calcificationswith poor enhancement. MRI showed that anterior mediastinal mass showed intermediate signal intensity on T1-weighted images (T1WI), high SIon T2-weighted images (T2WI), and heterogeneous enhancement. Biopsy was performed and the anterior mediastinal tumor was diagnosed asthymic mucinous adenocarcinoma by histopathologic examination and immunohistochemical staining.

CONCLUSION: Thymic mucinous adenocarcinomas could be included in differential diagnoses of anterior mediastinal tumors showing extensive calcification, andcommon imaging findings of mucinous adenocarcinoma such as T2 high signal intensity and heterogeneous enhancement on MRI may be helpfulto diagnose thymic mucinous adenocarcinoma.

Medienart:

E-Artikel

Erscheinungsjahr:

2024

2023

Erschienen:

2024

Enthalten in:

Zur Gesamtaufnahme - volume:20

Enthalten in:

Current medical imaging - 20(2023) vom: 05., Seite e060623217707

Sprache:

Englisch

Beteiligte Personen:

Cho, Hangjun [VerfasserIn]
Park, Jongmin [VerfasserIn]
Shin, Kyung Min [VerfasserIn]
Park, Seo Young [VerfasserIn]
Park, Byunggeon [VerfasserIn]
Jeong, Ji Yun [VerfasserIn]
Kim, Jae-Hui [VerfasserIn]

Links:

Volltext

Themen:

Adenocarcinoma
Calcification
Case Reports
Computed tomography
Magnetic resonance imaging
Mucinous
Thymus

Anmerkungen:

Date Completed 14.11.2023

Date Revised 22.11.2023

published: Print

Citation Status MEDLINE

doi:

10.2174/1573405620666230606125454

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM357845285