Applications of trimetallic nanomaterials as Non-Enzymatic glucose sensors

OBJECTIVE: This article critically reviews recent research on the use of trimetallic nanomaterials for the fabrication of non-enzymatic glucose sensors (NEGS), also known as fourth-generation glucose sensors (FGGS).

SIGNIFICANCE: Diabetes is a prevalent chronic disease worldwide, and glucose monitoring is crucial for its management. However, conventional enzymatic glucose sensors suffer from several technological drawbacks, and there is a need to develop new-generation glucose sensors that can overcome these limitations. NEGS, particularly those composed of trimetallic nanocomposites, have demonstrated promising results in terms of improved shelf life, higher sensitivity, and simplicity of operation during glucose measurement.

METHODS: In this review, we discuss the different trimetallic nanomaterials developed and used by researchers in recent years for glucose detection, including their mechanisms of action. We also provide a brief discussion of the advantages and disadvantages of FGGS-based trimetallic nanomaterials, as well as the industrial challenges in this area of research.

RESULTS: Trimetallic nanomaterials for FGGS have shown excellent reproducibility and high stability, making them suitable for continuous glucose monitoring. The different types of trimetallic nanomaterials have varying sensing properties, and their performance can be tuned by controlling their synthesis parameters.

CONCLUSION: Trimetallic nanomaterials are a promising avenue for the development of FGGS, recent research has demonstrated their potential for glucose monitoring. However, there are still some challenges that need to be addressed before their widespread adoption, such as their long-term stability and cost-effectiveness. Further research in this area is needed to overcome these challenges and to develop commercially viable FGGS for diabetes management.

Medienart:

E-Artikel

Erscheinungsjahr:

2023

Erschienen:

2023

Enthalten in:

Zur Gesamtaufnahme - volume:49

Enthalten in:

Drug development and industrial pharmacy - 49(2023), 6 vom: 16. Juni, Seite 393-404

Sprache:

Englisch

Beteiligte Personen:

Hassan, Israr U [VerfasserIn]
Naikoo, Gowhar A [VerfasserIn]
Arshad, Fareeha [VerfasserIn]
Ba Omar, Fatima [VerfasserIn]
Aljabali, Alaa A A [VerfasserIn]
Mishra, Vijay [VerfasserIn]
Mishra, Yachana [VerfasserIn]
El-Tanani, Mohamed [VerfasserIn]
Charbe, Nitin B [VerfasserIn]
Chava, Sai Raghuveer [VerfasserIn]
Serrano-Aroca, Ángel [VerfasserIn]
Tambuwala, Murtaza M [VerfasserIn]

Links:

Volltext

Themen:

Blood Glucose
Diabetes
Fourth-generation glucose sensors
Glucose
IY9XDZ35W2
Journal Article
Review
Trimetallic nanomaterials

Anmerkungen:

Date Completed 21.07.2023

Date Revised 21.07.2023

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1080/03639045.2023.2221737

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM357746953