Subclinical enthesitis in enthesitis-related arthritis and sacroiliitis associated with familial Mediterranean fever

© Japan College of Rheumatology 2023. Published by Oxford University Press..

OBJECTIVES: In our study, we investigated the presence of subclinical enthesitis by ultrasonography (US) in asymptomatic patients with enthesitis-related arthritis (ERA) and sacroiliitis associated with familial Mediterranean fever (FMF).

METHODS: A total of 50 patients, including 35 patients with ERA and 15 with sacroiliitis associated with FMF, were included in the study. All patients were evaluated with US by a paediatric radiologist. Enthesis of seven tendons (common extensor and flexor tendons, quadriceps tendon, proximal and distal patellar tendon, Achilles tendon, and plantar fascia) was examined on both sides.

RESULTS: Subclinical enthesitis was detected in 10 ERA (28.5%) and three FMF (20%) patients. Enthesitis was radiologically diagnosed in 16 (2.3%) out of 700 evaluated entheseal sites. The most frequent sites of enthesitis were Achilles (37.5%) and quadriceps (31.3%) tendons. All patients were in clinical remission and had no active complaints, and acute phase reactants were within normal limits. Therefore, the patients were followed up without treatment change. However, disease flare-up was observed in three of these patients (23.1%) during the follow-up, and their treatments were intensified.

CONCLUSIONS: Our results showed that the US can be particularly helpful in detecting subclinical enthesitis and predicting disease flare-ups.

Medienart:

E-Artikel

Erscheinungsjahr:

2024

Erschienen:

2024

Enthalten in:

Zur Gesamtaufnahme - volume:34

Enthalten in:

Modern rheumatology - 34(2024), 3 vom: 28. März, Seite 607-613

Sprache:

Englisch

Beteiligte Personen:

Sener, Seher [VerfasserIn]
Atalay, Erdal [VerfasserIn]
Yildiz, Adalet Elcin [VerfasserIn]
Kasap Cuceoglu, Muserref [VerfasserIn]
Basaran, Ozge [VerfasserIn]
Batu, Ezgi Deniz [VerfasserIn]
Bilginer, Yelda [VerfasserIn]
Ozen, Seza [VerfasserIn]

Links:

Volltext

Themen:

Enthesitis-related arthritis
Familial Mediterranean fever
Journal Article
Subclinical enthesitis
Tendons
Ultrasonography

Anmerkungen:

Date Completed 29.03.2024

Date Revised 11.04.2024

published: Print

Citation Status MEDLINE

doi:

10.1093/mr/road053

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM357692314