Prediction of Linear B Cell Epitopes in Proteins
© 2023. The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature..
The accurate prediction of B cell epitopes is crucial for the design and development of vaccines, especially of those preventive for emerging pathogenic diseases. Preventive vaccines are mainly based on the induction of highly specific neutralizing antibodies. This chapter deals with some prediction methods, which are currently available as user-friendly online servers, to predict B cell epitopes in proteins. A final assessment to validate these predictions is done by recurring to the Immune Epitope Database (IEDB).
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:2673 |
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| Enthalten in: |
Methods in molecular biology (Clifton, N.J.) - 2673(2023) vom: 31., Seite 189-196 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
de Los Toyos, Juan R [VerfasserIn] |
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| Links: |
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| Themen: |
Epitopes, B-Lymphocyte |
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| Anmerkungen: |
Date Completed 02.06.2023 Date Revised 06.06.2023 published: Print Citation Status MEDLINE |
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| doi: |
10.1007/978-1-0716-3239-0_13 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| 520 | |a The accurate prediction of B cell epitopes is crucial for the design and development of vaccines, especially of those preventive for emerging pathogenic diseases. Preventive vaccines are mainly based on the induction of highly specific neutralizing antibodies. This chapter deals with some prediction methods, which are currently available as user-friendly online servers, to predict B cell epitopes in proteins. A final assessment to validate these predictions is done by recurring to the Immune Epitope Database (IEDB) | ||
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