Predictive value of a positive stress single-photon emission computed tomography or stress cardiac magnetic resonance for ruling in obstructive coronary artery disease in a real-world setting
Copyright © 2023 Sociedade Portuguesa de Cardiologia. Publicado por Elsevier España, S.L.U. All rights reserved..
INTRODUCTION AND OBJECTIVES: Randomized controlled trials comparing stress cardiac magnetic resonance (CMR) and single-photon emission computed tomography (SPECT) suggest similar diagnostic accuracy for detecting obstructive coronary artery disease (CAD). There are few data on whether this remains true in routine clinical practice. The aim of this study was to assess clinical and angiographic characteristics of patients undergoing invasive coronary angiography (ICA) after stress CMR or SPECT, and to compare their positive predictive value with published results from the CE-MARC trial.
METHODS: In this retrospective tertiary-center analysis, we included 429 patients undergoing ICA after a positive stress CMR or positive SPECT performed within the previous 12 months. Obstructive CAD was defined as any coronary artery stenosis ≥50% in a vessel compatible with the ischemic territory on stress testing.
RESULTS: Of the total 429 patients, 356 (83%) were referred after a positive SPECT, and 73 (17%) after a positive stress CMR. Patients did not differ according to age, cardiovascular risk factors, previous revascularization or left ventricular dysfunction, but patients with SPECT were more frequently male (p=0.046). The prevalence of obstructive CAD was similar in patients with positive SPECT vs. positive stress CMR (76.1% vs. 80.8%, respectively, p=0.385). The positive predictive values of both techniques were similar to those reported in the CE-MARC trial.
CONCLUSION: In this tertiary center analysis, stress CMR and SPECT showed similar positive predictive values, comparable to those reported in the CE-MARC trial. This finding supports the emerging adoption of CMR in clinical practice for the diagnosis and management of CAD.
| Errataetall: |
CommentIn: Rev Port Cardiol. 2023 Sep;42(9):795-796. - PMID 37263499 |
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| Medienart: |
E-Artikel |
| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:42 |
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| Enthalten in: |
Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology - 42(2023), 9 vom: 01. Sept., Seite 787-793 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Silva, Cláudia [VerfasserIn] |
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| Anmerkungen: |
Date Completed 06.09.2023 Date Revised 12.09.2023 published: Print-Electronic CommentIn: Rev Port Cardiol. 2023 Sep;42(9):795-796. - PMID 37263499 Citation Status MEDLINE |
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| doi: |
10.1016/j.repc.2023.01.026 |
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| PPN (Katalog-ID): |
NLM357597052 |
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| 245 | 1 | 0 | |a Predictive value of a positive stress single-photon emission computed tomography or stress cardiac magnetic resonance for ruling in obstructive coronary artery disease in a real-world setting |
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| 500 | |a Date Completed 06.09.2023 | ||
| 500 | |a Date Revised 12.09.2023 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a CommentIn: Rev Port Cardiol. 2023 Sep;42(9):795-796. - PMID 37263499 | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright © 2023 Sociedade Portuguesa de Cardiologia. Publicado por Elsevier España, S.L.U. All rights reserved. | ||
| 520 | |a INTRODUCTION AND OBJECTIVES: Randomized controlled trials comparing stress cardiac magnetic resonance (CMR) and single-photon emission computed tomography (SPECT) suggest similar diagnostic accuracy for detecting obstructive coronary artery disease (CAD). There are few data on whether this remains true in routine clinical practice. The aim of this study was to assess clinical and angiographic characteristics of patients undergoing invasive coronary angiography (ICA) after stress CMR or SPECT, and to compare their positive predictive value with published results from the CE-MARC trial | ||
| 520 | |a METHODS: In this retrospective tertiary-center analysis, we included 429 patients undergoing ICA after a positive stress CMR or positive SPECT performed within the previous 12 months. Obstructive CAD was defined as any coronary artery stenosis ≥50% in a vessel compatible with the ischemic territory on stress testing | ||
| 520 | |a RESULTS: Of the total 429 patients, 356 (83%) were referred after a positive SPECT, and 73 (17%) after a positive stress CMR. Patients did not differ according to age, cardiovascular risk factors, previous revascularization or left ventricular dysfunction, but patients with SPECT were more frequently male (p=0.046). The prevalence of obstructive CAD was similar in patients with positive SPECT vs. positive stress CMR (76.1% vs. 80.8%, respectively, p=0.385). The positive predictive values of both techniques were similar to those reported in the CE-MARC trial | ||
| 520 | |a CONCLUSION: In this tertiary center analysis, stress CMR and SPECT showed similar positive predictive values, comparable to those reported in the CE-MARC trial. This finding supports the emerging adoption of CMR in clinical practice for the diagnosis and management of CAD | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Cardiovascular magnetic resonance | |
| 650 | 4 | |a Cintigrafia de perfusão miocárdica | |
| 650 | 4 | |a Doença arterial coronária obstrutiva | |
| 650 | 4 | |a Obstructive coronary artery disease | |
| 650 | 4 | |a Positive predictive value | |
| 650 | 4 | |a Ressonância magnética cardíaca | |
| 650 | 4 | |a Single-photon emission computed tomography | |
| 650 | 4 | |a Valor preditivo positivo | |
| 700 | 1 | |a Lopes, Pedro |e verfasserin |4 aut | |
| 700 | 1 | |a Gonçalves, Mariana |e verfasserin |4 aut | |
| 700 | 1 | |a Ventosa, António |e verfasserin |4 aut | |
| 700 | 1 | |a Calqueiro, João |e verfasserin |4 aut | |
| 700 | 1 | |a Freitas, Pedro |e verfasserin |4 aut | |
| 700 | 1 | |a Guerreiro, Sara |e verfasserin |4 aut | |
| 700 | 1 | |a Brito, João |e verfasserin |4 aut | |
| 700 | 1 | |a Abecasis, João |e verfasserin |4 aut | |
| 700 | 1 | |a Raposo, Luís |e verfasserin |4 aut | |
| 700 | 1 | |a Saraiva, Carla |e verfasserin |4 aut | |
| 700 | 1 | |a de Araújo Gonçalves, Pedro |e verfasserin |4 aut | |
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| 700 | 1 | |a Campante Teles, Rui |e verfasserin |4 aut | |
| 700 | 1 | |a de Sousa Almeida, Manuel |e verfasserin |4 aut | |
| 700 | 1 | |a Ferreira, António Miguel |e verfasserin |4 aut | |
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