Pulvinar neuromodulation for seizure monitoring and network modulation in temporal plus epilepsy
© 2023 The Authors. Annals of Clinical and Translational Neurology published by Wiley Periodicals LLC on behalf of American Neurological Association..
Deep brain stimulation (DBS) is a promising treatment for drug-refractory epilepsies (DRE) when targeting the anterior nuclei of thalamus (ANT). However, targeting other thalamic nuclei, such as the pulvinar, shows therapeutic promise. Our pioneering case study presents the application of ambulatory seizure monitoring using spectral fingerprinting (12.15-17.15 Hz) recorded through Medtronic Percept DBS implanted bilaterally in the medial pulvinar thalami. This technology offers unprecedented opportunities for real-time monitoring of seizure burden and thalamocortical network modulation for effective seizure reduction in patients with bilateral mesial temporal and temporal plus epilepsies that are not suitable for resection.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:10 |
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| Enthalten in: |
Annals of clinical and translational neurology - 10(2023), 7 vom: 27. Juli, Seite 1254-1259 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Vakilna, Yash Shashank [VerfasserIn] |
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| Links: |
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| Themen: |
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| Anmerkungen: |
Date Completed 19.07.2023 Date Revised 20.07.2023 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1002/acn3.51815 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM357339037 |
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| 245 | 1 | 0 | |a Pulvinar neuromodulation for seizure monitoring and network modulation in temporal plus epilepsy |
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| 500 | |a Citation Status MEDLINE | ||
| 520 | |a © 2023 The Authors. Annals of Clinical and Translational Neurology published by Wiley Periodicals LLC on behalf of American Neurological Association. | ||
| 520 | |a Deep brain stimulation (DBS) is a promising treatment for drug-refractory epilepsies (DRE) when targeting the anterior nuclei of thalamus (ANT). However, targeting other thalamic nuclei, such as the pulvinar, shows therapeutic promise. Our pioneering case study presents the application of ambulatory seizure monitoring using spectral fingerprinting (12.15-17.15 Hz) recorded through Medtronic Percept DBS implanted bilaterally in the medial pulvinar thalami. This technology offers unprecedented opportunities for real-time monitoring of seizure burden and thalamocortical network modulation for effective seizure reduction in patients with bilateral mesial temporal and temporal plus epilepsies that are not suitable for resection | ||
| 650 | 4 | |a Case Reports | |
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| 700 | 1 | |a Hafeez, Muhammad Ubaid |e verfasserin |4 aut | |
| 700 | 1 | |a Ilyas, Adeel |e verfasserin |4 aut | |
| 700 | 1 | |a Saranathan, Manojkumar |e verfasserin |4 aut | |
| 700 | 1 | |a Gavvala, Jay |e verfasserin |4 aut | |
| 700 | 1 | |a Tandon, Nitin |e verfasserin |4 aut | |
| 700 | 1 | |a Pati, Sandipan |e verfasserin |4 aut | |
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