Cost-effectiveness of Lifestyle Africa : an adaptation of the diabetes prevention programme for delivery by community health workers in urban South Africa
BACKGROUND: Lifestyle Africa is an adapted version of the Diabetes Prevention Program designed for delivery by community health workers to socioeconomically disadvantaged populations in low- and middle-income countries (LMICs). Results from the Lifestyle Africa trial conducted in an under-resourced community in South Africa indicated that the programme had a significant effect on reducing haemoglobin A1c (HbA1c).
OBJECTIVE: To estimate the cost of implementation and the cost-effectiveness (in cost per point reduction in HbA1c) of the Lifestyle Africa programme to inform decision-makers of the resources required and the value of this intervention.
METHODS: Interviews were held with project administrators to identify the activities and resources required to implement the intervention. A direct-measure micro-costing approach was used to determine the number of units and unit cost for each resource. The incremental cost per one point improvement in HbA1c was calculated.
RESULTS: The intervention equated to 71 United States dollars (USD) in implementation costs per participant and a 0.26 improvement in HbA1c per participant.
CONCLUSIONS: Lifestyle Africa reduced HbA1c for relatively little cost and holds promise for addressing chronic disease in LMIC. Decision-makers should consider the comparative clinical effectiveness and cost-effectiveness of this intervention when making resource allocation decisions.
TRIAL REGISTRATION: Trial registration is at ClinicalTrials.gov (NCT03342274).
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2023 |
|---|---|
| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:16 |
|---|---|
| Enthalten in: |
Global health action - 16(2023), 1 vom: 31. Dez., Seite 2212952 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Whittington, Melanie D [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
Economic analysis |
|---|
| Anmerkungen: |
Date Completed 25.05.2023 Date Revised 07.02.2024 published: Print ClinicalTrials.gov: NCT03342274 Citation Status MEDLINE |
|---|
| doi: |
10.1080/16549716.2023.2212952 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM357225295 |
|---|
| LEADER | 01000caa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM357225295 | ||
| 003 | DE-627 | ||
| 005 | 20240207232016.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231226s2023 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1080/16549716.2023.2212952 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1283.xml |
| 035 | |a (DE-627)NLM357225295 | ||
| 035 | |a (NLM)37220094 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Whittington, Melanie D |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Cost-effectiveness of Lifestyle Africa |b an adaptation of the diabetes prevention programme for delivery by community health workers in urban South Africa |
| 264 | 1 | |c 2023 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 25.05.2023 | ||
| 500 | |a Date Revised 07.02.2024 | ||
| 500 | |a published: Print | ||
| 500 | |a ClinicalTrials.gov: NCT03342274 | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a BACKGROUND: Lifestyle Africa is an adapted version of the Diabetes Prevention Program designed for delivery by community health workers to socioeconomically disadvantaged populations in low- and middle-income countries (LMICs). Results from the Lifestyle Africa trial conducted in an under-resourced community in South Africa indicated that the programme had a significant effect on reducing haemoglobin A1c (HbA1c) | ||
| 520 | |a OBJECTIVE: To estimate the cost of implementation and the cost-effectiveness (in cost per point reduction in HbA1c) of the Lifestyle Africa programme to inform decision-makers of the resources required and the value of this intervention | ||
| 520 | |a METHODS: Interviews were held with project administrators to identify the activities and resources required to implement the intervention. A direct-measure micro-costing approach was used to determine the number of units and unit cost for each resource. The incremental cost per one point improvement in HbA1c was calculated | ||
| 520 | |a RESULTS: The intervention equated to 71 United States dollars (USD) in implementation costs per participant and a 0.26 improvement in HbA1c per participant | ||
| 520 | |a CONCLUSIONS: Lifestyle Africa reduced HbA1c for relatively little cost and holds promise for addressing chronic disease in LMIC. Decision-makers should consider the comparative clinical effectiveness and cost-effectiveness of this intervention when making resource allocation decisions | ||
| 520 | |a TRIAL REGISTRATION: Trial registration is at ClinicalTrials.gov (NCT03342274) | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Research Support, N.I.H., Extramural | |
| 650 | 4 | |a Economic analysis | |
| 650 | 4 | |a HbA1c | |
| 650 | 4 | |a lifestyle interventions | |
| 650 | 4 | |a low- and middle-income countries | |
| 650 | 4 | |a probabilistic sensitivity analysis | |
| 650 | 7 | |a Glycated Hemoglobin |2 NLM | |
| 700 | 1 | |a Goggin, Kathy |e verfasserin |4 aut | |
| 700 | 1 | |a Tsolekile, Lungiswa |e verfasserin |4 aut | |
| 700 | 1 | |a Puoane, Thandi |e verfasserin |4 aut | |
| 700 | 1 | |a Fox, Andrew T |e verfasserin |4 aut | |
| 700 | 1 | |a Resnicow, Ken |e verfasserin |4 aut | |
| 700 | 1 | |a Fleming, Kandace K |e verfasserin |4 aut | |
| 700 | 1 | |a Smyth, Joshua M |e verfasserin |4 aut | |
| 700 | 1 | |a Materia, Frank T |e verfasserin |4 aut | |
| 700 | 1 | |a Hurley, Emily A |e verfasserin |4 aut | |
| 700 | 1 | |a Vitolins, Mara Z |e verfasserin |4 aut | |
| 700 | 1 | |a Lambert, Estelle V |e verfasserin |4 aut | |
| 700 | 1 | |a Levitt, Naomi S |e verfasserin |4 aut | |
| 700 | 1 | |a Catley, Delwyn |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Global health action |d 2008 |g 16(2023), 1 vom: 31. Dez., Seite 2212952 |w (DE-627)NLM193914522 |x 1654-9880 |7 nnns |
| 773 | 1 | 8 | |g volume:16 |g year:2023 |g number:1 |g day:31 |g month:12 |g pages:2212952 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1080/16549716.2023.2212952 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 16 |j 2023 |e 1 |b 31 |c 12 |h 2212952 | ||