Burden of migraine in patients attending Belgian headache specialists : real-world evidence from the BECOME study
© 2023. The Author(s) under exclusive licence to Belgian Neurological Society..
INTRODUCTION: Migraine is a primary headache disorder, which imposes a major burden on the sufferers. The BECOME study (Burden of migrainE in specialist headache Centers treating patients with prOphylactic treatMent failurE) attempted to characterize and assess the prevalence, burden and healthcare resource utilization of migraine patients presenting in specialized headache centers in Europe and Israel. In this paper, we will describe the patient characteristics of the Belgian headache centers.
METHODS: The BECOME study was a prospective, non-interventional, cross-sectional study consisting of two parts. In the first part of the study, data were collected from subjects with a diagnosis of migraine. Subsequently, patients with ≥ 4 monthly migraine days (MMD) and ≥ 1 prior preventive treatment failure (PPTF) filled out validated questionnaires to assess the burden of disease.
RESULTS: In part 1 of the Belgian study population (N = 806), 45% of patients reported ≥ 8 MMD and 25% had failed ≥ 4 preventive treatments. In part 2 (N = 90), more than 90% of patients reported having severe impact of headache on daily life and having severe migraine-related disability. The impact was the highest for patients with ≥ 15 MMD, however, even within the patient population with < 8 MMD, the burden was significant. Almost 40% of the study population suffered from anxiety.
CONCLUSIONS: These findings in the Belgian sample of the BECOME study demonstrate the substantial burden and unmet need for the management of difficult-to-treat migraine.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2023 |
|---|---|
| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:123 |
|---|---|
| Enthalten in: |
Acta neurologica Belgica - 123(2023), 4 vom: 20. Aug., Seite 1495-1503 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Lourens, Shantaily [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
Burden |
|---|
| Anmerkungen: |
Date Completed 14.07.2023 Date Revised 18.07.2023 published: Print-Electronic Citation Status MEDLINE |
|---|
| doi: |
10.1007/s13760-023-02280-4 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM357117646 |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM357117646 | ||
| 003 | DE-627 | ||
| 005 | 20231226071912.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231226s2023 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1007/s13760-023-02280-4 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1190.xml |
| 035 | |a (DE-627)NLM357117646 | ||
| 035 | |a (NLM)37209257 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Lourens, Shantaily |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Burden of migraine in patients attending Belgian headache specialists |b real-world evidence from the BECOME study |
| 264 | 1 | |c 2023 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 14.07.2023 | ||
| 500 | |a Date Revised 18.07.2023 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a © 2023. The Author(s) under exclusive licence to Belgian Neurological Society. | ||
| 520 | |a INTRODUCTION: Migraine is a primary headache disorder, which imposes a major burden on the sufferers. The BECOME study (Burden of migrainE in specialist headache Centers treating patients with prOphylactic treatMent failurE) attempted to characterize and assess the prevalence, burden and healthcare resource utilization of migraine patients presenting in specialized headache centers in Europe and Israel. In this paper, we will describe the patient characteristics of the Belgian headache centers | ||
| 520 | |a METHODS: The BECOME study was a prospective, non-interventional, cross-sectional study consisting of two parts. In the first part of the study, data were collected from subjects with a diagnosis of migraine. Subsequently, patients with ≥ 4 monthly migraine days (MMD) and ≥ 1 prior preventive treatment failure (PPTF) filled out validated questionnaires to assess the burden of disease | ||
| 520 | |a RESULTS: In part 1 of the Belgian study population (N = 806), 45% of patients reported ≥ 8 MMD and 25% had failed ≥ 4 preventive treatments. In part 2 (N = 90), more than 90% of patients reported having severe impact of headache on daily life and having severe migraine-related disability. The impact was the highest for patients with ≥ 15 MMD, however, even within the patient population with < 8 MMD, the burden was significant. Almost 40% of the study population suffered from anxiety | ||
| 520 | |a CONCLUSIONS: These findings in the Belgian sample of the BECOME study demonstrate the substantial burden and unmet need for the management of difficult-to-treat migraine | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Burden | |
| 650 | 4 | |a Migraine | |
| 650 | 4 | |a Patient-reported outcomes | |
| 650 | 4 | |a Treatment failure | |
| 700 | 1 | |a Van Deun, Laura |e verfasserin |4 aut | |
| 700 | 1 | |a Peeters, Ilse |e verfasserin |4 aut | |
| 700 | 1 | |a Paemeleire, Koen |e verfasserin |4 aut | |
| 700 | 1 | |a Van Dycke, Annelies |e verfasserin |4 aut | |
| 700 | 1 | |a De Klippel, Nina |e verfasserin |4 aut | |
| 700 | 1 | |a Schoenen, Jean |e verfasserin |4 aut | |
| 700 | 1 | |a Ritter, Shannon |e verfasserin |4 aut | |
| 700 | 1 | |a Snellman, Josefin |e verfasserin |4 aut | |
| 700 | 1 | |a Versijpt, Jan |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Acta neurologica Belgica |d 1970 |g 123(2023), 4 vom: 20. Aug., Seite 1495-1503 |w (DE-627)NLM000045705 |x 2240-2993 |7 nnns |
| 773 | 1 | 8 | |g volume:123 |g year:2023 |g number:4 |g day:20 |g month:08 |g pages:1495-1503 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1007/s13760-023-02280-4 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 123 |j 2023 |e 4 |b 20 |c 08 |h 1495-1503 | ||