Dynamic of irisin secretion change after moderate-intensity chronic physical exercise on obese female

© 2023 Walter de Gruyter GmbH, Berlin/Boston..

OBJECTIVES: Exercise is one of the beneficial mediators for the regulation and prevention of obesity through the role of irisin, so it potentially enhances metabolism health. This study aims to investigate the dynamic of irisin secrecy change after chronic exercise in obese females.

METHODS: Thirty-one female adolescents aged 20-22 years enrolled in the study and were given interventions aerobic, resistance, and a combination of aerobic and resistance training. The exercises were performed at moderate-intensity, for 35-40 min per session, and three times a week for four weeks. The measurement of irisin level, IGF-1 level, and bio-anthropometry was carried out before and after the four weeks of exercise. The bio-anthropometry measurement was carried out using seca mBCA 514, while the measurement of insulin-like growth factor 1 (IGF-1) and irisin was completed using an enzyme-linked immunosorbent assay (ELISA). The obtained data were analyzed using a one-way ANOVA test with 5 % significance.

RESULTS: Our results indicated higher dynamic of irisin and IGF-1 increases in the group with a combination of aerobic and resistance training exercises than the other two groups with a different exercise. Further, we also observed different dynamics of irisin and IGF-1 level increase (p<0.05). Besides, the irisin was also correlated with the IGF-1 and bio-anthropometric parameters (p<0.05).

CONCLUSIONS: The combination of aerobic and resistance training exercises is considered as the alternative for enhancing the dynamic of irisin and IGF-1 increase. Thus, it can be used to prevent and regulate obesity.

Media Type:

Electronic Article

Year of Publication:

2023

Publication:

2023

Contained In:

To Main Record - volume:34

Contained In:

Journal of basic and clinical physiology and pharmacology - 34(2023), 4 vom: 01. Juli, Seite 539-547

Language:

English

Contributors:

Merawati, Desiana [Author]
Sugiharto [Author]
Susanto, Hendra [Author]
Taufiq, Ahmad [Author]
Pranoto, Adi [Author]
Amelia, Dessy [Author]
Rejeki, Purwo Sri [Author]

Links:

Volltext

Keywords:

67763-96-6
Aerobic training
FNDC5 protein, human
Fibronectins
Insulin-Like Growth Factor I
Journal Article
Metabolism health
Obesity
Resistance training

Notes:

Date Completed 03.08.2023

Date Revised 03.08.2023

published: Electronic-eCollection

Citation Status MEDLINE

doi:

10.1515/jbcpp-2023-0041

funding:

Supporting institution / Project title:

PPN (Catalogue-ID):

NLM357115163