An International, Multicenter Evaluation of Comprehensive Medication Management by Pharmacists in ICU Recovery Centers

BACKGROUND: Post-intensive care syndrome (PICS) is defined as a new or worsening impairment in physical, cognitive, or mental health following critical illness. Intensive care unit recovery centers (ICU-RC) are one means to treat patients who have PICS. The purpose of this study is to describe the role of pharmacists in ICU-RCs.

RESEARCH QUESTION: What is the number and type of medication interventions made by a pharmacist at an ICU-RC at 12 different centers?.

STUDY DESIGN AND METHODS: This prospective, observational study was conducted in 12 intensive care units (ICUs)/ICU-RCs between September 2019 and July 2021. A full medication review was conducted by a pharmacist on patients seen at the ICU-RC.

RESULTS: 507 patients were referred to the ICU-RC. Of these patients, 474 attended the ICU-RC and 472 had a full medication review performed by a pharmacist. Baseline demographic and hospital course data were obtained from the electronic health record and at the ICU-RC appointment. Pharmacy interventions were made in 397 (84%) patients. The median number of pharmacy interventions per patient was 2 (interquartile range [IQR] = 1,3). Medications were stopped and started in 124 (26%) and 91 (19%) patients, respectively. The number of patients that had a dose decreased and a dose increased was 51 (11%) and 43 (9%), respectively. There was no difference in the median total number of medications that the patient was prescribed at the start and end of the patient visit (10, IQR = 5, 15). Adverse drug event (ADE) preventive measures were implemented in 115 (24%) patients. ADE events were identified in 69 (15%) patients. Medication interactions were identified in 30 (6%) patients.

INTERPRETATION: A pharmacist plays an integral role in an ICU-RC resulting in the identification, prevention, and treatment of medication-related problems. This paper should serve as a call to action on the importance of the inclusion of a pharmacist in ICU-RC clinics.

Medienart:

E-Artikel

Erscheinungsjahr:

2023

Erschienen:

2023

Enthalten in:

Zur Gesamtaufnahme - volume:38

Enthalten in:

Journal of intensive care medicine - 38(2023), 10 vom: 31. Okt., Seite 957-965

Sprache:

Englisch

Beteiligte Personen:

Stollings, Joanna L [VerfasserIn]
Poyant, Janelle O [VerfasserIn]
Groth, Christine M [VerfasserIn]
Rappaport, Stephen H [VerfasserIn]
Kruer, Rachel M [VerfasserIn]
Miller, Emily [VerfasserIn]
Whitten, Jessica A [VerfasserIn]
Mcintire, Allyson M [VerfasserIn]
McDaniel, Cara M [VerfasserIn]
Betthauser, Kevin D [VerfasserIn]
Mohammad, Rima A [VerfasserIn]
Kenes, Michael T [VerfasserIn]
Korona, Rebecca Bookstavar [VerfasserIn]
Barber, Alexandra E [VerfasserIn]
MacTavish, Pamela [VerfasserIn]
Dixit, Deepali [VerfasserIn]
Yeung, Siu Yan A [VerfasserIn]

Links:

Volltext

Themen:

Adverse drug event
Journal Article
Medication reconciliation
Multicenter Study
Observational Study
Pharmacist
Post-intensive care syndrome
Post-intensive care syndrome clinic

Anmerkungen:

Date Completed 26.09.2023

Date Revised 26.09.2023

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1177/08850666231176194

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM357014995