Transcatheter Aortic Valve Implantation in Cardiac Amyloidosis and Aortic Stenosis
Copyright © 2023 Elsevier Inc. All rights reserved..
Aortic stenosis (AS) and cardiac amyloidosis (CA) occur concomitantly in a significant number of patients and portend a higher risk of all-cause mortality. Previous studies have investigated outcomes in patients with concomitant CA/AS who underwent transcatheter aortic valve implantation (TAVI) versus medical therapy alone, but no evidence-based consensus regarding the ideal management of these patients has been established. Medline, Scopus, and Cochrane Central Register of Controlled Trials were systematically searched to identify relevant studies. Methodologic bias was assessed using the modified Newcastle-Ottawa scale for observational studies. A total of 4 observational studies comprising 83 patients were included. Of these, 45 patients (54%) underwent TAVI, whereas 38 (46%) were managed conservatively. Of the 3 studies that included baseline characteristics by treatment group, 30% were women. The risk of all-cause mortality was found to be significantly lower in patients who underwent TAVI than those treated with conservative medical therapy alone (odds ratio 0.24, 95% confidence interval 0.08 to 0.73). In conclusion, this meta-analysis suggests a lower risk of all-cause mortality in patients with CA with AS who underwent TAVI than those managed with medical therapy alone.
| Errataetall: |
CommentIn: Am J Cardiol. 2023 Aug 1;200:144-145. - PMID 37321027 |
|---|---|
| Medienart: |
E-Artikel |
| Erscheinungsjahr: |
2023 |
|---|---|
| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:198 |
|---|---|
| Enthalten in: |
The American journal of cardiology - 198(2023) vom: 01. Juli, Seite 101-107 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Riley, Joshua M [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
|---|
| Anmerkungen: |
Date Completed 13.06.2023 Date Revised 18.11.2023 published: Print-Electronic CommentIn: Am J Cardiol. 2023 Aug 1;200:144-145. - PMID 37321027 Citation Status MEDLINE |
|---|
| doi: |
10.1016/j.amjcard.2023.04.003 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM356858529 |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM356858529 | ||
| 003 | DE-627 | ||
| 005 | 20231226071343.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231226s2023 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1016/j.amjcard.2023.04.003 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1189.xml |
| 035 | |a (DE-627)NLM356858529 | ||
| 035 | |a (NLM)37183091 | ||
| 035 | |a (PII)S0002-9149(23)00202-3 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Riley, Joshua M |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Transcatheter Aortic Valve Implantation in Cardiac Amyloidosis and Aortic Stenosis |
| 264 | 1 | |c 2023 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 13.06.2023 | ||
| 500 | |a Date Revised 18.11.2023 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a CommentIn: Am J Cardiol. 2023 Aug 1;200:144-145. - PMID 37321027 | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright © 2023 Elsevier Inc. All rights reserved. | ||
| 520 | |a Aortic stenosis (AS) and cardiac amyloidosis (CA) occur concomitantly in a significant number of patients and portend a higher risk of all-cause mortality. Previous studies have investigated outcomes in patients with concomitant CA/AS who underwent transcatheter aortic valve implantation (TAVI) versus medical therapy alone, but no evidence-based consensus regarding the ideal management of these patients has been established. Medline, Scopus, and Cochrane Central Register of Controlled Trials were systematically searched to identify relevant studies. Methodologic bias was assessed using the modified Newcastle-Ottawa scale for observational studies. A total of 4 observational studies comprising 83 patients were included. Of these, 45 patients (54%) underwent TAVI, whereas 38 (46%) were managed conservatively. Of the 3 studies that included baseline characteristics by treatment group, 30% were women. The risk of all-cause mortality was found to be significantly lower in patients who underwent TAVI than those treated with conservative medical therapy alone (odds ratio 0.24, 95% confidence interval 0.08 to 0.73). In conclusion, this meta-analysis suggests a lower risk of all-cause mortality in patients with CA with AS who underwent TAVI than those managed with medical therapy alone | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Meta-Analysis | |
| 700 | 1 | |a Junarta, Joey |e verfasserin |4 aut | |
| 700 | 1 | |a Ullah, Waqas |e verfasserin |4 aut | |
| 700 | 1 | |a Siddiqui, Muhammad U |e verfasserin |4 aut | |
| 700 | 1 | |a Anzelmi, Alexander |e verfasserin |4 aut | |
| 700 | 1 | |a Ruge, Max |e verfasserin |4 aut | |
| 700 | 1 | |a Vishnevsky, Alec |e verfasserin |4 aut | |
| 700 | 1 | |a Alvarez, Rene J |e verfasserin |4 aut | |
| 700 | 1 | |a Ruggiero, Nicholas J |e verfasserin |4 aut | |
| 700 | 1 | |a Rajapreyar, Indranee N |e verfasserin |4 aut | |
| 700 | 1 | |a Brailovsky, Yevgeniy |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t The American journal of cardiology |d 1958 |g 198(2023) vom: 01. Juli, Seite 101-107 |w (DE-627)NLM000025364 |x 1879-1913 |7 nnns |
| 773 | 1 | 8 | |g volume:198 |g year:2023 |g day:01 |g month:07 |g pages:101-107 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1016/j.amjcard.2023.04.003 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 198 |j 2023 |b 01 |c 07 |h 101-107 | ||