Allergen exposure boosts peripheral Th9 responses in patients with local allergic rhinitis

© 2023 The Authors. International Forum of Allergy & Rhinology published by Wiley Periodicals LLC on behalf of American Academy of Otolaryngic Allergy and American Rhinologic Society..

KEY POINTS: Intranasal allergen exposure increases peripheral total Th2 and Th9 cells in patients with local allergic rhinitis (LAR). Peripheral T-cell response seems dominated by Th9 cells in patients with LAR, whereas Th2 responses prevail in patients with allergic rhinitis. Our results identify Th9 cells as potential therapeutic targets for patients with LAR.

Medienart:

E-Artikel

Erscheinungsjahr:

2023

Erschienen:

2023

Enthalten in:

Zur Gesamtaufnahme - volume:13

Enthalten in:

International forum of allergy & rhinology - 13(2023), 11 vom: 07. Nov., Seite 2086-2091

Sprache:

Englisch

Beteiligte Personen:

Palomares, Francisca [VerfasserIn]
Testera-Montes, Almudena [VerfasserIn]
Aranda, Carlos Jose [VerfasserIn]
Alba-Linero, Carmen [VerfasserIn]
Sáenz de Santa María-García, Rocío [VerfasserIn]
Bentabol-Ramos, Guillermo [VerfasserIn]
Mayorga, Cristobalina [VerfasserIn]
Torres, Maria Jose [VerfasserIn]
Rondon, Carmen [VerfasserIn]
Eguiluz-Gracia, Ibon [VerfasserIn]

Links:

Volltext

Themen:

Allergens
Allergic rhinitis
Biomarker
Inhalation allergen challenge
Journal Article
Rhinitis
Therapeutics

Anmerkungen:

Date Revised 23.10.2023

published: Print-Electronic

Citation Status Publisher

doi:

10.1002/alr.23175

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM356540480