Recent Advances in the Development of Membrane-derived Vesicles for Cancer Immunotherapy

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The surface proteins on cell membranes enable the cells to have different properties, such as high biocompatibility, surface modifiability, and homologous targeting ability. Cell-membrane-derived vesicles have features identical to those of their parental cells, which makes them one of the most promising materials for drug delivery. Recently, as a result of the impressive effects of immunotherapy in cancer treatment, an increasing number of researchers have used cell-membrane-derived vesicles to enhance immune responses. To be more specific, the membrane vesicles derived from immune cells, tumor cells, bacteria, or engineered cells have the antigen presentation capacity and can trigger strong anti-tumor effects of the immune system. In this review, we first indicated a brief description of the vesicles and then introduced the detection technology and drug-loading methods for them. Secondly, we concluded the characteristics and applications of vesicles derived from different sources in cancer immunotherapy.

Medienart:

E-Artikel

Erscheinungsjahr:

2024

2023

Erschienen:

2024

Enthalten in:

Zur Gesamtaufnahme - volume:21

Enthalten in:

Current drug delivery - 21(2023), 3 vom: 01., Seite 403-420

Sprache:

Englisch

Beteiligte Personen:

Xiao, Yuai [VerfasserIn]
Wu, Minliang [VerfasserIn]
Xue, Chunyu [VerfasserIn]
Wang, Yuchong [VerfasserIn]

Links:

Volltext

Themen:

Cancer immunotherapy
Drug delivery
Extracellular vesicles
Immune response
Journal Article
Nanovesicles
Review
Therapeutic agents.

Anmerkungen:

Date Completed 23.11.2023

Date Revised 23.11.2023

published: Print

Citation Status MEDLINE

doi:

10.2174/1567201820666230504120841

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM356465020