3D Printing Approaches to Engineer Cardiac Tissue

© 2023. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature..

PURPOSE OF REVIEW: Bioengineering of functional cardiac tissue composed of primary cardiomyocytes has great potential for myocardial regeneration and in vitro tissue modeling. 3D bioprinting was developed to create cardiac tissue in hydrogels that can mimic the structural, physiological, and functional features of native myocardium. Through a detailed review of the 3D printing technologies and bioink materials used in the creation of a heart tissue, this article discusses the potential of engineered heart tissues in biomedical applications.

RECENT FINDINGS: In this review, we discussed the recent progress in 3D bioprinting strategies for cardiac tissue engineering, including bioink and 3D bioprinting methods as well as examples of engineered cardiac tissue such as in vitro cardiac models and vascular channels. 3D printing is a powerful tool for creating in vitro cardiac tissues that are structurally and functionally similar to real tissues. The use of human-induced pluripotent stem cell-derived cardiomyocytes (iPSC-CM) enables the generation of patient-specific tissues. These tissues have the potential to be used for regenerative therapies, disease modeling, and drug testing.

Medienart:

E-Artikel

Erscheinungsjahr:

2023

Erschienen:

2023

Enthalten in:

Zur Gesamtaufnahme - volume:25

Enthalten in:

Current cardiology reports - 25(2023), 6 vom: 02. Juni, Seite 505-514

Sprache:

Englisch

Beteiligte Personen:

Lu, Ting-Yu [VerfasserIn]
Xiang, Yi [VerfasserIn]
Tang, Min [VerfasserIn]
Chen, Shaochen [VerfasserIn]

Links:

Volltext

Themen:

3D printing
Bioink
Journal Article
Research Support, N.I.H., Extramural
Research Support, U.S. Gov't, Non-P.H.S.
Review
Tissue engineering
Tissue modeling

Anmerkungen:

Date Completed 18.05.2023

Date Revised 19.05.2023

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1007/s11886-023-01881-y

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM356330877