Prevalence of latent Mycobacterium tuberculosis infection in hematopoietic stem cell transplantation comparing tuberculin skin test and interferon-gamma release assay
© 2023. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature..
The aim of this study was to evaluate the prevalence of latent Mycobacterium tuberculosis infection in hematopoietic stem cell transplantation candidates, using tuberculin skin test and QuantiFERON-TB Gold-Plus, in a high-burden tuberculosis country. Adult candidates for hematopoietic stem cell transplantation performed both tests before and those submitted to transplantation were followed up for 12 months. The prevalence of latent Mycobacterium tuberculosis infection was 17.1% and a moderate agreement between QuantiFERON-TB Gold-Plus and tuberculin skin test was observed in this population. Previous tuberculosis exposure was a risk factor for latent Mycobacterium tuberculosis infection. No cases of tuberculosis were diagnosed during follow-up period.
Medienart: |
E-Artikel |
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Erscheinungsjahr: |
2023 |
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Erschienen: |
2023 |
Enthalten in: |
Zur Gesamtaufnahme - volume:42 |
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Enthalten in: |
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology - 42(2023), 7 vom: 01. Juli, Seite 899-902 |
Sprache: |
Englisch |
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Beteiligte Personen: |
Castro-Lima, Victor A C [VerfasserIn] |
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Links: |
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Themen: |
Hematopoietic stem cell transplantation |
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Anmerkungen: |
Date Completed 16.06.2023 Date Revised 16.06.2023 published: Print-Electronic Citation Status MEDLINE |
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doi: |
10.1007/s10096-023-04613-w |
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funding: |
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Förderinstitution / Projekttitel: |
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PPN (Katalog-ID): |
NLM356294994 |
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520 | |a The aim of this study was to evaluate the prevalence of latent Mycobacterium tuberculosis infection in hematopoietic stem cell transplantation candidates, using tuberculin skin test and QuantiFERON-TB Gold-Plus, in a high-burden tuberculosis country. Adult candidates for hematopoietic stem cell transplantation performed both tests before and those submitted to transplantation were followed up for 12 months. The prevalence of latent Mycobacterium tuberculosis infection was 17.1% and a moderate agreement between QuantiFERON-TB Gold-Plus and tuberculin skin test was observed in this population. Previous tuberculosis exposure was a risk factor for latent Mycobacterium tuberculosis infection. No cases of tuberculosis were diagnosed during follow-up period | ||
650 | 4 | |a Journal Article | |
650 | 4 | |a Hematopoietic stem cell transplantation | |
650 | 4 | |a Immunocompromised host | |
650 | 4 | |a Interferon-gamma release tests | |
650 | 4 | |a Tuberculin | |
650 | 4 | |a Tuberculosis | |
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700 | 1 | |a Costa, Silvia F |e verfasserin |4 aut | |
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