Inpatient cardiovascular outcomes in patients with cancer affected by viral influenza infection
© The Author(s) 2022. Published by Oxford University Press on behalf of Postgraduate Medical Journal. All rights reserved. For permissions, please e-mail: journals.permissionsoup.com..
BACKGROUND: Influenza disproportionately affects individuals with underlying comorbidities. Long-term follow-up studies have shown that patients with cancer with influenza have higher mortality. However, very little is known about the in-hospital mortality and cardiovascular outcomes of influenza infection in cancer hospitalisations.
METHODS: We compared the in-hospital mortality and cardiovascular outcomes in patients with cancer with and without influenza by screening the National Inpatient Sample from 2015 to 2017. A total of 9 443 421 hospitalisations with any cancer were identified, out of which 14 634 had influenza while 9 252 007 did not. A two-level hierarchical multivariate logistic regression analysis adjusted for age, sex, race, hospital type and relevant comorbidities was performed.
RESULTS: The group with cancer and influenza had higher in-hospital mortality (OR 1.08; 95% CI 1.003 to 1.16; p=0.04), acute coronary syndromes (OR 1.74; 95% CI 1.57 to 1.93; p<0.0001), atrial fibrillation (OR 1.24; 95% CI 1.18 to 1.29; p<0.0001) and acute heart failure (OR 1.41; 95% CI 1.32 to 1.51; p<0.0001).
CONCLUSION: Patients with cancer affected by influenza have higher in-hospital mortality and a higher prevalence of acute coronary syndrome, atrial fibrillation and acute heart failure.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2022 |
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| Erschienen: |
2022 |
| Enthalten in: |
Zur Gesamtaufnahme - year:2022 |
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| Enthalten in: |
Postgraduate medical journal - (2022) vom: 02. Sept. |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Sheth, Aakash R [VerfasserIn] |
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| Links: |
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| Themen: |
Adult cardiology |
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| Anmerkungen: |
Date Revised 24.04.2023 published: Print-Electronic Citation Status Publisher |
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| doi: |
10.1136/postmj/pmj-2022-141738 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM355992701 |
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| 520 | |a © The Author(s) 2022. Published by Oxford University Press on behalf of Postgraduate Medical Journal. All rights reserved. For permissions, please e-mail: journals.permissionsoup.com. | ||
| 520 | |a BACKGROUND: Influenza disproportionately affects individuals with underlying comorbidities. Long-term follow-up studies have shown that patients with cancer with influenza have higher mortality. However, very little is known about the in-hospital mortality and cardiovascular outcomes of influenza infection in cancer hospitalisations | ||
| 520 | |a METHODS: We compared the in-hospital mortality and cardiovascular outcomes in patients with cancer with and without influenza by screening the National Inpatient Sample from 2015 to 2017. A total of 9 443 421 hospitalisations with any cancer were identified, out of which 14 634 had influenza while 9 252 007 did not. A two-level hierarchical multivariate logistic regression analysis adjusted for age, sex, race, hospital type and relevant comorbidities was performed | ||
| 520 | |a RESULTS: The group with cancer and influenza had higher in-hospital mortality (OR 1.08; 95% CI 1.003 to 1.16; p=0.04), acute coronary syndromes (OR 1.74; 95% CI 1.57 to 1.93; p<0.0001), atrial fibrillation (OR 1.24; 95% CI 1.18 to 1.29; p<0.0001) and acute heart failure (OR 1.41; 95% CI 1.32 to 1.51; p<0.0001) | ||
| 520 | |a CONCLUSION: Patients with cancer affected by influenza have higher in-hospital mortality and a higher prevalence of acute coronary syndrome, atrial fibrillation and acute heart failure | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a adult cardiology | |
| 650 | 4 | |a adult oncology | |
| 650 | 4 | |a cardiology | |
| 650 | 4 | |a myocardial infarction | |
| 650 | 4 | |a public health | |
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| 700 | 1 | |a Patel, Harsh P |e verfasserin |4 aut | |
| 700 | 1 | |a Thotamgari, Sahith Reddy |e verfasserin |4 aut | |
| 700 | 1 | |a Patel, Smit |e verfasserin |4 aut | |
| 700 | 1 | |a Desai, Rohan |e verfasserin |4 aut | |
| 700 | 1 | |a Thakkar, Samarthkumar |e verfasserin |4 aut | |
| 700 | 1 | |a Papayannis, Aristotelis |e verfasserin |4 aut | |
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