Treatment and Outcome of Osteoporotic Thoracolumbar Vertebral Body Fractures With Deformation of Both Endplates With or Without Posterior Wall Involvement (OF 4) : Short-Term Results from the Prospective EOFTT Multicenter Study
STUDY DESIGN: Multicenter prospective cohort study.
OBJECTIVE: To analyse therapeutical strategies applied to osteoporotic thoracolumbar OF 4 injuries, to assess related complications and clinical outcome.
METHODS: A multicenter prospective cohort study (EOFTT) including 518 consecutive patients who were treated for an Osteoporotic vertebral compression fracture (OVCF). For the present study, only patients with OF 4 fractures were analysed. Outcome parameters were complications, Visual Analogue Scale, Oswestry Disability Questionnaire, Timed Up & Go test, EQ-5D 5L, and Barthel Index after a minimum follow-up of 6 weeks.
RESULTS: A total of 152 (29%) patients presented with OF 4 fractures with a mean age of 76 years (range 41-97). The most common treatment was short-segment posterior stabilization (51%; hybrid stabilization in 36%). Mean follow up was 208 days (±131 days), mean ODI was 30 ± 21. Dorsoventral stabilized patients were younger compared to the other groups (P < .001) and had significant better TuG compared to hybrid stabilization (P = .049). The other clinical outcomes did not differ in the therapy strategies (VAS pain: P = 1.000, ODI: P > .602, Barthel: P > .252, EQ-5D 5L index value: P > .610, VAS-EQ-5D 5L: P = 1.000). The inpatient complication rate was 8% after conservative and 16% after surgical treatment. During follow-up period 14% of conservatively treated patients and 3% of surgical treated patients experienced neurological deficits.
CONCLUSIONS: Conservative therapy of OF 4 injuries seems to be viable option in patients with only moderate symptoms. Hybrid stabilization was the dominant treatment strategy leading to promising clinical short-term results. Stand-alone cement augmentation seems to be a valid alternative in selected cases.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:13 |
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| Enthalten in: |
Global spine journal - 13(2023), 1_suppl vom: 01. Apr., Seite 36S-43S |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Spiegl, Ulrich J A [VerfasserIn] |
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| Links: |
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| Themen: |
Journal Article |
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| Anmerkungen: |
Date Revised 15.05.2023 published: Print Citation Status PubMed-not-MEDLINE |
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| doi: |
10.1177/21925682221140831 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM355881055 |
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| 100 | 1 | |a Spiegl, Ulrich J A |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Treatment and Outcome of Osteoporotic Thoracolumbar Vertebral Body Fractures With Deformation of Both Endplates With or Without Posterior Wall Involvement (OF 4) |b Short-Term Results from the Prospective EOFTT Multicenter Study |
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| 500 | |a Date Revised 15.05.2023 | ||
| 500 | |a published: Print | ||
| 500 | |a Citation Status PubMed-not-MEDLINE | ||
| 520 | |a STUDY DESIGN: Multicenter prospective cohort study | ||
| 520 | |a OBJECTIVE: To analyse therapeutical strategies applied to osteoporotic thoracolumbar OF 4 injuries, to assess related complications and clinical outcome | ||
| 520 | |a METHODS: A multicenter prospective cohort study (EOFTT) including 518 consecutive patients who were treated for an Osteoporotic vertebral compression fracture (OVCF). For the present study, only patients with OF 4 fractures were analysed. Outcome parameters were complications, Visual Analogue Scale, Oswestry Disability Questionnaire, Timed Up & Go test, EQ-5D 5L, and Barthel Index after a minimum follow-up of 6 weeks | ||
| 520 | |a RESULTS: A total of 152 (29%) patients presented with OF 4 fractures with a mean age of 76 years (range 41-97). The most common treatment was short-segment posterior stabilization (51%; hybrid stabilization in 36%). Mean follow up was 208 days (±131 days), mean ODI was 30 ± 21. Dorsoventral stabilized patients were younger compared to the other groups (P < .001) and had significant better TuG compared to hybrid stabilization (P = .049). The other clinical outcomes did not differ in the therapy strategies (VAS pain: P = 1.000, ODI: P > .602, Barthel: P > .252, EQ-5D 5L index value: P > .610, VAS-EQ-5D 5L: P = 1.000). The inpatient complication rate was 8% after conservative and 16% after surgical treatment. During follow-up period 14% of conservatively treated patients and 3% of surgical treated patients experienced neurological deficits | ||
| 520 | |a CONCLUSIONS: Conservative therapy of OF 4 injuries seems to be viable option in patients with only moderate symptoms. Hybrid stabilization was the dominant treatment strategy leading to promising clinical short-term results. Stand-alone cement augmentation seems to be a valid alternative in selected cases | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a OF classification | |
| 650 | 4 | |a operative | |
| 650 | 4 | |a osteoporosis | |
| 650 | 4 | |a spine | |
| 650 | 4 | |a vertebral fracture | |
| 700 | 1 | |a Schenk, Philipp |e verfasserin |4 aut | |
| 700 | 1 | |a Schnake, Klaus John |e verfasserin |4 aut | |
| 700 | 1 | |a Ullrich, Bernhard W |e verfasserin |4 aut | |
| 700 | 1 | |a Osterhoff, Georg |e verfasserin |4 aut | |
| 700 | 1 | |a Scheyerer, Max J |e verfasserin |4 aut | |
| 700 | 1 | |a Schmeiser, Gregor |e verfasserin |4 aut | |
| 700 | 1 | |a Bäumlein, Martin |e verfasserin |4 aut | |
| 700 | 1 | |a Scherer, Michael A |e verfasserin |4 aut | |
| 700 | 1 | |a Müller, Michael |e verfasserin |4 aut | |
| 700 | 1 | |a Sprengel, Kai |e verfasserin |4 aut | |
| 700 | 1 | |a Liepold, Katja |e verfasserin |4 aut | |
| 700 | 1 | |a Schramm, Simon |e verfasserin |4 aut | |
| 700 | 1 | |a Baron, H-Christopher |e verfasserin |4 aut | |
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| 700 | 1 | |a Schwarz, Falko |e verfasserin |4 aut | |
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| 700 | 1 | |a Zimmermann, Volker |e verfasserin |4 aut | |
| 700 | 1 | |a Katscher, Sebastian |e verfasserin |4 aut | |
| 700 | 0 | |a Working Group Osteoporotic Fractures of the Spine Section of the German Society of Orthopaedics and Trauma |e verfasserin |4 aut | |
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