The role of corticosteroids in patients hospitalized for COVID-19 at Mexico general Hospital

Copyright: © 2023 Permanyer..

OBJECTIVE: To compare the evolution of hospitalized patients infected with SARS-CoV-2 who received corticosteroid-based treatment versus patients who received standard therapy.

METHOD: Retrospective, observational, and analytical study. Clinical records were collected from the different intensive care units, and data were obtained from confirmed COVID-19 patients over 18 years of age who were hospitalized. The population was divided into two groups: patients who received corticosteroid treatment, and those who received standard therapy.

RESULTS: A total of 1603 patients were admitted to hospital, and of these 984 (62.9%) were discharged due to death. The main result was the identification by odds ratio (OR: 4.68; 95% confidence interval [95% CI]: 3.75-5.83; p = 0.001) as risk for death to the use of systemic steroids, as well as the use of invasive mechanical ventilation (OR: 2.26; 95% CI: 1.80-2.82; p < 0.001). The male gender was the most affected with 1051 (65.6%) patients. Mean age was 56 years (± 14).

CONCLUSIONS: Corticosteroid use was associated with poor prognosis in patients hospitalized for COVID-19 compared to those receiving standard therapy.

Medienart:

E-Artikel

Erscheinungsjahr:

2023

Erschienen:

2023

Enthalten in:

Zur Gesamtaufnahme - volume:91

Enthalten in:

Cirugia y cirujanos - 91(2023), 2 vom: 01., Seite 233-239

Sprache:

Englisch

Weiterer Titel:

El papel de los corticoesteroides en pacientes hospitalizados por COVID-19 en el Hospital General de México

Beteiligte Personen:

Iturbide-Mauricio, Leonel [VerfasserIn]
Palacios-Vaca, Jessica [VerfasserIn]
Calleja-López, Jesús R [VerfasserIn]
Pérez-Navarro, Monserrat [VerfasserIn]
García-García, José A [VerfasserIn]
Espinosa-García, Ana M [VerfasserIn]

Links:

Volltext

Themen:

Acute respiratory failure
Adrenal Cortex Hormones
COVID-19
Corticoesteroides
Corticosteroids
Insuficiencia respiratoria aguda
Journal Article
Mortalidad
Mortality
Observational Study

Anmerkungen:

Date Completed 25.04.2023

Date Revised 25.04.2023

published: Print

Citation Status MEDLINE

doi:

10.24875/CIRU.22000233

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM355880547