Diagnostic Performance of Magnetic Resonance Angiography for Artery Stenosis After Kidney Transplant : A Systematic Review and Meta-Analysis

Copyright © 2023 The Association of University Radiologists. Published by Elsevier Inc. All rights reserved..

RATIONALE AND OBJECTIVES: Magnetic resonance angiography (MRA) is used to diagnose artery stenosis after kidney transplant. However, there is a lack of applicable consensus guidelines, and the diagnostic value of this technique is unclear. Therefore, the aim of the present study was to evaluate the diagnostic performance of MRA for the detection of artery stenosis after kidney transplant.

MATERIALS AND METHODS: We searched PubMed, Web of Science, Cochrane Library, and Embase from database inception to September 1, 2022. Two independent reviewers assessed the methodological quality of eligible studies using the quality assessment of diagnostic accuracy studies-2 tool. The diagnostic odds ratio, pooled sensitivity, and specificity values, positive likelihood ratios, and negative likelihood ratios were calculated to synthesize data with a bivariate random-effects model. Meta-regression analysis was performed in cases of high among-study heterogeneity.

RESULTS: Eleven studies were included in the meta-analysis. The area under the summary receiver operating characteristic curve was 0.96 (95% confidence interval [CI]: 0.94-0.98). The pooled sensitivity and specificity values for MRA in diagnosing artery stenosis after kidney transplant were 0.96 (95% CI: 0.76-0.99) and 0.93 (95% CI: 0.86-0.96), respectively.

CONCLUSION: MRA demonstrated high sensitivity and specificity for diagnosing artery stenosis after kidney transplant, suggesting that it may be used reliably in clinical practice. However, further large-scale studies are required to validate the present findings.

Medienart:

E-Artikel

Erscheinungsjahr:

2023

Erschienen:

2023

Enthalten in:

Zur Gesamtaufnahme - volume:30

Enthalten in:

Academic radiology - 30(2023), 9 vom: 23. Sept., Seite 2021-2030

Sprache:

Englisch

Beteiligte Personen:

Huang, Yao [VerfasserIn]
Zhang, Bin [VerfasserIn]
Zheng, Jieling [VerfasserIn]
Ma, Xiao [VerfasserIn]
Zhang, Shuixing [VerfasserIn]
Chen, Qiuying [VerfasserIn]

Links:

Volltext

Themen:

Diagnosis
Journal Article
Kidney transplant
Magnetic resonance angiography
Meta-Analysis
Renal artery
Review
Systematic Review

Anmerkungen:

Date Completed 25.08.2023

Date Revised 31.08.2023

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1016/j.acra.2023.02.034

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM355801973