Looking back on the COVID-19 pandemic in an elite sports team using whole genome sequencing
Copyright © 2023 The Authors. Published by Elsevier Ltd.. All rights reserved..
OBJECTIVES: The aim of this study was to investigate the effectiveness of infection control measures to prevent transmission of SARS-CoV-2 within a professional sports team using whole genome sequencing.
DESIGN: Prospective cohort study.
METHODS: 74 players and staff members of a Dutch professional male football team were followed from August 2020 until May 2021. A set of health and safety measures were introduced and all participants underwent regular SARS-CoV-2 RNA testing. All positive samples were subsequently sequenced (Nanopore sequencing) to assess whether infections were acquired within the training center or in the community.
RESULTS: Throughout the study period, 13 participants tested positive for SARS-CoV-2. The phylogenetic analysis revealed 2 clusters (of 2 and 3 cases respectively), indicating that 3/13 cases (23%) acquired infection from another player or staff member. The first cluster was diagnosed upon enrolment, thus transmission had occurred prior to the implementation of health and safety protocols. Finally, 4 cases were diagnosed prior to symptom onset, emphasizing that frequent testing leads to early detection and isolation.
CONCLUSIONS: These data show that a combination of regular testing and basic control measures can prevent outbreaks of COVID-19 in a professional sports team. Whole genome sequencing is an important tool to distinguish between infections introduced from the community and infections transmitted between athletes.
| Errataetall: |
CommentIn: J Sci Med Sport. 2023 Apr-May;26(4-5):217. - PMID 37302812 |
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| Medienart: |
E-Artikel |
| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:26 |
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| Enthalten in: |
Journal of science and medicine in sport - 26(2023), 4-5 vom: 01. Apr., Seite 218-221 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Shamier, Marc C [VerfasserIn] |
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| Links: |
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| Themen: |
COVID-19 |
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| Anmerkungen: |
Date Completed 13.06.2023 Date Revised 14.06.2023 published: Print-Electronic CommentIn: J Sci Med Sport. 2023 Apr-May;26(4-5):217. - PMID 37302812 Citation Status MEDLINE |
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| doi: |
10.1016/j.jsams.2023.03.010 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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NLM355655179 |
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| 500 | |a published: Print-Electronic | ||
| 500 | |a CommentIn: J Sci Med Sport. 2023 Apr-May;26(4-5):217. - PMID 37302812 | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright © 2023 The Authors. Published by Elsevier Ltd.. All rights reserved. | ||
| 520 | |a OBJECTIVES: The aim of this study was to investigate the effectiveness of infection control measures to prevent transmission of SARS-CoV-2 within a professional sports team using whole genome sequencing | ||
| 520 | |a DESIGN: Prospective cohort study | ||
| 520 | |a METHODS: 74 players and staff members of a Dutch professional male football team were followed from August 2020 until May 2021. A set of health and safety measures were introduced and all participants underwent regular SARS-CoV-2 RNA testing. All positive samples were subsequently sequenced (Nanopore sequencing) to assess whether infections were acquired within the training center or in the community | ||
| 520 | |a RESULTS: Throughout the study period, 13 participants tested positive for SARS-CoV-2. The phylogenetic analysis revealed 2 clusters (of 2 and 3 cases respectively), indicating that 3/13 cases (23%) acquired infection from another player or staff member. The first cluster was diagnosed upon enrolment, thus transmission had occurred prior to the implementation of health and safety protocols. Finally, 4 cases were diagnosed prior to symptom onset, emphasizing that frequent testing leads to early detection and isolation | ||
| 520 | |a CONCLUSIONS: These data show that a combination of regular testing and basic control measures can prevent outbreaks of COVID-19 in a professional sports team. Whole genome sequencing is an important tool to distinguish between infections introduced from the community and infections transmitted between athletes | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a COVID-19 | |
| 650 | 4 | |a Prevention | |
| 650 | 4 | |a Whole genome sequencing | |
| 650 | 7 | |a RNA, Viral |2 NLM | |
| 700 | 1 | |a Wismans, Leonoor V |e verfasserin |4 aut | |
| 700 | 1 | |a van Boheemen, Sander |e verfasserin |4 aut | |
| 700 | 1 | |a Oude Munnink, Bas B |e verfasserin |4 aut | |
| 700 | 1 | |a Koopmans, Marion P G |e verfasserin |4 aut | |
| 700 | 1 | |a van Eijck, Casper H J |e verfasserin |4 aut | |
| 700 | 1 | |a van der Eijk, Annemiek A |e verfasserin |4 aut | |
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