L-Tartaric Acid Inhibits Diminazene-induced Vasorelaxation in Isolated Rat Aorta

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AIMS: The study investigated the effect of L-tartaric acid on diminazene-indiuced vasorelaxation.

BACKGROUND: Diminazene is known to induce vasorelaxation through the stimulation of angiotensin-converting enzyme (ACE-2).

OBJECTIVE: This work was designed to study the effect of L-tartaric acid on diminazene-induced vasorelaxation using an ex vivo approach.

MATERIAL AND METHODS: In the current investigation, the inhibitory effect of L-tartaric acid on diminazene-induced relaxation.

RESULTS: The results confirmed that L-tartaric acid was able to inhibit in a dose-dependent manner diminazene-induced vasorelaxation.

CONCLUSION: This investigation provides important experimental evidence of the efficacy of L-tartaric acid in inhibiting diminazene-induced vasorelaxation.

Medienart:

E-Artikel

Erscheinungsjahr:

2023

Erschienen:

2023

Enthalten in:

Zur Gesamtaufnahme - year:2023

Enthalten in:

Cardiovascular & hematological agents in medicinal chemistry - (2023) vom: 06. Apr.

Sprache:

Englisch

Beteiligte Personen:

Amssayef, Ayoub [VerfasserIn]
Bouadid, Ismail [VerfasserIn]
Eddouks, Mohamed [VerfasserIn]

Links:

Volltext

Themen:

ACE-2
Aorta ring.
COVID-19
Diminazene
Ex vivo
Journal Article
L-Tartaric acid

Anmerkungen:

Date Revised 11.04.2023

published: Print-Electronic

Citation Status Publisher

doi:

10.2174/1871525721666230406075646

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM355432269