Causes of Childhood Blindness in the United States Using the IRIS® Registry (Intelligent Research in Sight)
Copyright © 2023 American Academy of Ophthalmology. Published by Elsevier Inc. All rights reserved..
PURPOSE: To investigate causes of childhood blindness in the United States using the IRIS® Registry (Intelligent Research in Sight).
DESIGN: Cross-sectional study.
PARTICIPANTS: Patients ≤ 18 years of age with visual acuity (VA) 20/200 or worse in their better-seeing eye in the IRIS Registry during 2018.
METHODS: Causes of blindness were classified by anatomic site and specific diagnoses.
MAIN OUTCOME MEASURES: Percentages of causes of blindness.
RESULTS: Of 81 164 children with 2018 VA data in the IRIS Registry, 961 (1.18%) had VA 20/200 or worse in their better-seeing eye. Leading causes of blindness were retinopathy of prematurity (ROP) in 301 patients (31.3%), nystagmus in 78 patients (8.1%), and cataract in 64 patients (6.7%). The retina was the leading anatomic site (47.7%) followed by optic nerve (11.6%) and lens (10.0%). A total of 52.4% of patients had treatable causes of blindness.
CONCLUSIONS: This analysis offers a unique cross-sectional view of childhood blindness in the United States using a clinical data registry. More than one-half of blind patients had a treatable cause of blindness.
FINANCIAL DISCLOSURE(S): Proprietary or commercial disclosure may be found in the Footnotes and Disclosures at the end of this article.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2023 |
|---|---|
| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:130 |
|---|---|
| Enthalten in: |
Ophthalmology - 130(2023), 9 vom: 01. Sept., Seite 907-913 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Lim, Han Woong [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
Childhood blindness |
|---|
| Anmerkungen: |
Date Completed 22.08.2023 Date Revised 05.10.2023 published: Print-Electronic Citation Status MEDLINE |
|---|
| doi: |
10.1016/j.ophtha.2023.04.004 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM355419041 |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM355419041 | ||
| 003 | DE-627 | ||
| 005 | 20231226064314.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231226s2023 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1016/j.ophtha.2023.04.004 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1184.xml |
| 035 | |a (DE-627)NLM355419041 | ||
| 035 | |a (NLM)37037315 | ||
| 035 | |a (PII)S0161-6420(23)00245-2 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Lim, Han Woong |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Causes of Childhood Blindness in the United States Using the IRIS® Registry (Intelligent Research in Sight) |
| 264 | 1 | |c 2023 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 22.08.2023 | ||
| 500 | |a Date Revised 05.10.2023 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright © 2023 American Academy of Ophthalmology. Published by Elsevier Inc. All rights reserved. | ||
| 520 | |a PURPOSE: To investigate causes of childhood blindness in the United States using the IRIS® Registry (Intelligent Research in Sight) | ||
| 520 | |a DESIGN: Cross-sectional study | ||
| 520 | |a PARTICIPANTS: Patients ≤ 18 years of age with visual acuity (VA) 20/200 or worse in their better-seeing eye in the IRIS Registry during 2018 | ||
| 520 | |a METHODS: Causes of blindness were classified by anatomic site and specific diagnoses | ||
| 520 | |a MAIN OUTCOME MEASURES: Percentages of causes of blindness | ||
| 520 | |a RESULTS: Of 81 164 children with 2018 VA data in the IRIS Registry, 961 (1.18%) had VA 20/200 or worse in their better-seeing eye. Leading causes of blindness were retinopathy of prematurity (ROP) in 301 patients (31.3%), nystagmus in 78 patients (8.1%), and cataract in 64 patients (6.7%). The retina was the leading anatomic site (47.7%) followed by optic nerve (11.6%) and lens (10.0%). A total of 52.4% of patients had treatable causes of blindness | ||
| 520 | |a CONCLUSIONS: This analysis offers a unique cross-sectional view of childhood blindness in the United States using a clinical data registry. More than one-half of blind patients had a treatable cause of blindness | ||
| 520 | |a FINANCIAL DISCLOSURE(S): Proprietary or commercial disclosure may be found in the Footnotes and Disclosures at the end of this article | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Research Support, N.I.H., Extramural | |
| 650 | 4 | |a Research Support, Non-U.S. Gov't | |
| 650 | 4 | |a Childhood blindness | |
| 650 | 4 | |a IRIS registry | |
| 650 | 4 | |a Retinopathy of prematurity | |
| 700 | 1 | |a Pershing, Suzann |e verfasserin |4 aut | |
| 700 | 1 | |a Moshfeghi, Darius M |e verfasserin |4 aut | |
| 700 | 1 | |a Heo, Hwan |e verfasserin |4 aut | |
| 700 | 1 | |a Haque, Md Enamul |e verfasserin |4 aut | |
| 700 | 1 | |a Lambert, Scott R |e verfasserin |4 aut | |
| 700 | 0 | |a IRIS® Registry Analytic Center Consortium |e verfasserin |4 aut | |
| 700 | 1 | |a Pershing, Suzann |e investigator |4 oth | |
| 700 | 1 | |a Hyman, Leslie |e investigator |4 oth | |
| 700 | 1 | |a Haller, Julia A |e investigator |4 oth | |
| 700 | 1 | |a Lee, Aaron Y |e investigator |4 oth | |
| 700 | 1 | |a Lee, Cecilia S |e investigator |4 oth | |
| 700 | 1 | |a Lum, Flora |e investigator |4 oth | |
| 700 | 1 | |a Miller, Joan W |e investigator |4 oth | |
| 700 | 1 | |a Lorch, Alice |e investigator |4 oth | |
| 773 | 0 | 8 | |i Enthalten in |t Ophthalmology |d 1993 |g 130(2023), 9 vom: 01. Sept., Seite 907-913 |w (DE-627)NLM000457019 |x 1549-4713 |7 nnns |
| 773 | 1 | 8 | |g volume:130 |g year:2023 |g number:9 |g day:01 |g month:09 |g pages:907-913 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1016/j.ophtha.2023.04.004 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 130 |j 2023 |e 9 |b 01 |c 09 |h 907-913 | ||