Immunogenic molecules associated with gut bacterial cell walls : chemical structures, immune-modulating functions, and mechanisms
©The Author(s) 2023. Published by Oxford University Press on behalf of Higher Education Press..
Interactions between gut microbiome and host immune system are fundamental to maintaining the intestinal mucosal barrier and homeostasis. At the host-gut microbiome interface, cell wall-derived molecules from gut commensal bacteria have been reported to play a pivotal role in training and remodeling host immune responses. In this article, we review gut bacterial cell wall-derived molecules with characterized chemical structures, including peptidoglycan and lipid-related molecules that impact host health and disease processes via regulating innate and adaptive immunity. Also, we aim to discuss the structures, immune responses, and underlying mechanisms of these immunogenic molecules. Based on current advances, we propose cell wall-derived components as important sources of medicinal agents for the treatment of infection and immune diseases.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2023 |
|---|---|
| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:14 |
|---|---|
| Enthalten in: |
Protein & cell - 14(2023), 10 vom: 25. Okt., Seite 776-785 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Yin, Ruopeng [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
Gut commensal bacteria |
|---|
| Anmerkungen: |
Date Completed 27.10.2023 Date Revised 12.11.2023 published: Print Citation Status MEDLINE |
|---|
| doi: |
10.1093/procel/pwad016 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM355186276 |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM355186276 | ||
| 003 | DE-627 | ||
| 005 | 20231226063819.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231226s2023 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1093/procel/pwad016 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1183.xml |
| 035 | |a (DE-627)NLM355186276 | ||
| 035 | |a (NLM)37013853 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Yin, Ruopeng |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Immunogenic molecules associated with gut bacterial cell walls |b chemical structures, immune-modulating functions, and mechanisms |
| 264 | 1 | |c 2023 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 27.10.2023 | ||
| 500 | |a Date Revised 12.11.2023 | ||
| 500 | |a published: Print | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a ©The Author(s) 2023. Published by Oxford University Press on behalf of Higher Education Press. | ||
| 520 | |a Interactions between gut microbiome and host immune system are fundamental to maintaining the intestinal mucosal barrier and homeostasis. At the host-gut microbiome interface, cell wall-derived molecules from gut commensal bacteria have been reported to play a pivotal role in training and remodeling host immune responses. In this article, we review gut bacterial cell wall-derived molecules with characterized chemical structures, including peptidoglycan and lipid-related molecules that impact host health and disease processes via regulating innate and adaptive immunity. Also, we aim to discuss the structures, immune responses, and underlying mechanisms of these immunogenic molecules. Based on current advances, we propose cell wall-derived components as important sources of medicinal agents for the treatment of infection and immune diseases | ||
| 650 | 4 | |a Review | |
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a gut commensal bacteria | |
| 650 | 4 | |a immune responses | |
| 650 | 4 | |a lipid-related molecules | |
| 650 | 4 | |a peptidoglycan | |
| 700 | 1 | |a Wang, Tao |e verfasserin |4 aut | |
| 700 | 1 | |a Dai, Huanqin |e verfasserin |4 aut | |
| 700 | 1 | |a Han, Junjie |e verfasserin |4 aut | |
| 700 | 1 | |a Sun, Jingzu |e verfasserin |4 aut | |
| 700 | 1 | |a Liu, Ningning |e verfasserin |4 aut | |
| 700 | 1 | |a Dong, Wang |e verfasserin |4 aut | |
| 700 | 1 | |a Zhong, Jin |e verfasserin |4 aut | |
| 700 | 1 | |a Liu, Hongwei |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Protein & cell |d 2010 |g 14(2023), 10 vom: 25. Okt., Seite 776-785 |w (DE-627)NLM203729064 |x 1674-8018 |7 nnns |
| 773 | 1 | 8 | |g volume:14 |g year:2023 |g number:10 |g day:25 |g month:10 |g pages:776-785 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1093/procel/pwad016 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 14 |j 2023 |e 10 |b 25 |c 10 |h 776-785 | ||