Using "Age and Total-PSA" as the Main Indicators : The Results of Taizhou Integrated Prostate Screening (No 2)
The aim of the study was to analyze population-based prostate cancer (PCa) screening and the incidence of PCa among males ≥50 years of age residing in the Luqiao district of Taizhou, China. From October to December 2020, male residents ≥50 years of age were screened for serum total prostate-specific antigen (total-PSA). If t-PSA re-test levels persisted above 4 μg/L, subjects underwent further noninvasive examinations, including digital rectal examination or multiparameter magnetic resonance imaging (mpMRI) of the prostate. Subjects underwent prostate biopsy of pathological tissue based on t-PSA and mpMRI results. A total of 3524 (49.1%) residents participated in this PCa screening study. In total, 285 (8.1%) subjects exhibited t-PSA levels ≥4.0 μg/L and 112 (3.2%) underwent noninvasive examinations. Forty-two (1.2%) residents underwent prostate biopsy, of which 16 (0.45%) were diagnosed with PCa. Of those diagnosed with PCa, three (19%) had localized PCa (cT1-cT2N0M0), six (37%) had locally advanced PCa (cT3a- cT4N0-1M0), and seven (44%) had advanced metastatic PCa (M1). Unfortunately, 3477 (48.5%) residents did not participate in the study, mainly due to lack of awareness of PCa based on feedback from local health centers. Age and t-PSA were used as primary screening indicators and, when further combined with mpMRI and prostate biopsy, confirmed the diagnosis of PCa among participating residents. Although this was a relatively economical and convenient screening method, education and knowledge should be further enhanced to increase the participation rate in PCa screening programs.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:17 |
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| Enthalten in: |
American journal of men's health - 17(2023), 2 vom: 01. März, Seite 15579883231161292 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Zhu, Xiao-Liang [VerfasserIn] |
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| Links: |
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| Themen: |
EC 3.4.21.77 |
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| Anmerkungen: |
Date Completed 03.04.2023 Date Revised 25.04.2023 published: Print Citation Status MEDLINE |
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| doi: |
10.1177/15579883231161292 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM355030993 |
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| 100 | 1 | |a Zhu, Xiao-Liang |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Using "Age and Total-PSA" as the Main Indicators |b The Results of Taizhou Integrated Prostate Screening (No 2) |
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| 520 | |a The aim of the study was to analyze population-based prostate cancer (PCa) screening and the incidence of PCa among males ≥50 years of age residing in the Luqiao district of Taizhou, China. From October to December 2020, male residents ≥50 years of age were screened for serum total prostate-specific antigen (total-PSA). If t-PSA re-test levels persisted above 4 μg/L, subjects underwent further noninvasive examinations, including digital rectal examination or multiparameter magnetic resonance imaging (mpMRI) of the prostate. Subjects underwent prostate biopsy of pathological tissue based on t-PSA and mpMRI results. A total of 3524 (49.1%) residents participated in this PCa screening study. In total, 285 (8.1%) subjects exhibited t-PSA levels ≥4.0 μg/L and 112 (3.2%) underwent noninvasive examinations. Forty-two (1.2%) residents underwent prostate biopsy, of which 16 (0.45%) were diagnosed with PCa. Of those diagnosed with PCa, three (19%) had localized PCa (cT1-cT2N0M0), six (37%) had locally advanced PCa (cT3a- cT4N0-1M0), and seven (44%) had advanced metastatic PCa (M1). Unfortunately, 3477 (48.5%) residents did not participate in the study, mainly due to lack of awareness of PCa based on feedback from local health centers. Age and t-PSA were used as primary screening indicators and, when further combined with mpMRI and prostate biopsy, confirmed the diagnosis of PCa among participating residents. Although this was a relatively economical and convenient screening method, education and knowledge should be further enhanced to increase the participation rate in PCa screening programs | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Research Support, Non-U.S. Gov't | |
| 650 | 4 | |a Taizhou | |
| 650 | 4 | |a early prostate cancer screening | |
| 650 | 4 | |a magnetic resonance imaging | |
| 650 | 4 | |a prostate puncture | |
| 650 | 4 | |a prostate-specific antigen | |
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| 700 | 1 | |a Tung, Tao-Hsin |e verfasserin |4 aut | |
| 700 | 1 | |a Li, Haipin |e verfasserin |4 aut | |
| 700 | 1 | |a Wu, Songjiang |e verfasserin |4 aut | |
| 700 | 1 | |a Wang, Xianyou |e verfasserin |4 aut | |
| 700 | 1 | |a Wang, Lijun |e verfasserin |4 aut | |
| 700 | 1 | |a Zhang, Meixian |e verfasserin |4 aut | |
| 700 | 1 | |a Chen, Zhixia |e verfasserin |4 aut | |
| 700 | 1 | |a Liu, Dingyi |e verfasserin |4 aut | |
| 700 | 1 | |a Li, Feipin |e verfasserin |4 aut | |
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