Effect of Caffeine Consumption on Cardiovascular Disease : An Updated Review

© 2023. The Author(s), under exclusive licence to Springer Nature Switzerland AG..

The incidence of cardiovascular diseases has significantly increased with the expansion of the industrialization of societies, which is notably linked to lifestyle changes and an unhealthy diet. Hence, determining the healthiest diet habits and supplements seems to be an appropriate way to decrease the global burden of cardiovascular diseases. Currently, caffeine, one of the most widely consumed compounds in the world, has emerged with some promising results in the treatment of numerous pathophysiological conditions of cardiovascular diseases. A literature search was conducted in PubMed, Scopus, Science Direct, Google Scholar, and Web of Science databases for the relevant articles regarding the pharmacology, preclinical, and clinical studies on the potential effects of caffeine on cardiovascular diseases. While caffeine could improve cardiovascular outcomes through several mechanisms of action, the literature review revealed controversial clinical effects of caffeine on blood pressure, cardiac arrhythmias, acute coronary syndrome, stable angina, and heart failure. In the case of dyslipidemia, coffee consumption increased total cholesterol, triglyceride, and low-density lipoprotein. Taken together, the existence of multiple confounding factors in the caffeine studies has resulted in inconclusive data interpretation. Further well-designed studies with adequate control of the confounding factors are warranted to draw a clear conclusion on the cardiovascular efficacy and safety of caffeine.

Medienart:

E-Artikel

Erscheinungsjahr:

2023

Erschienen:

2023

Enthalten in:

Zur Gesamtaufnahme - volume:37

Enthalten in:

Pharmaceutical medicine - 37(2023), 2 vom: 30. März, Seite 139-151

Sprache:

Englisch

Beteiligte Personen:

Khiali, Sajad [VerfasserIn]
Agabalazadeh, Amin [VerfasserIn]
Sahrai, Hadi [VerfasserIn]
Bannazadeh Baghi, Hossein [VerfasserIn]
Rahbari Banaeian, Gholamreza [VerfasserIn]
Entezari-Maleki, Taher [VerfasserIn]

Links:

Volltext

Themen:

3G6A5W338E
Caffeine
Coffee
Journal Article
Review

Anmerkungen:

Date Completed 14.04.2023

Date Revised 03.05.2023

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1007/s40290-023-00466-y

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM355004437