T-cell lymphocytopenia : An omnipresent predictor of morbidity and mortality in consequence of SARS-CoV disease and influenza A infections
Copyright © 2023 Elsevier Ltd. All rights reserved..
PURPOSE OF THE RESEARCH: We proposed T-cell lymphocytopenia as a strategic predictor of serious coronavirus and influenza infections. Our preeminent goal was to determine whether a degree of T-cell lymphopenia would identify a distinct threshold cell count to differentiate between severe and non-severe infections. We codified an Index Severity Score to exploit an association between T-cell cytopenia and the grade of disease activity.
PRINCIPAL RESULT: A T-cell count of 560 cells/uL or below signified a trend towards advanced disease.
KEY FINDINGS AND CONCLUSIONS:.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:165 |
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| Enthalten in: |
Cytokine - 165(2023) vom: 30. Mai, Seite 156163 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Putter, Jeffrey S [VerfasserIn] |
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| Links: |
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| Themen: |
Index Severity Score of infection |
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| Anmerkungen: |
Date Completed 07.04.2023 Date Revised 17.04.2023 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1016/j.cyto.2023.156163 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| 500 | |a Date Revised 17.04.2023 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright © 2023 Elsevier Ltd. All rights reserved. | ||
| 520 | |a PURPOSE OF THE RESEARCH: We proposed T-cell lymphocytopenia as a strategic predictor of serious coronavirus and influenza infections. Our preeminent goal was to determine whether a degree of T-cell lymphopenia would identify a distinct threshold cell count to differentiate between severe and non-severe infections. We codified an Index Severity Score to exploit an association between T-cell cytopenia and the grade of disease activity | ||
| 520 | |a PRINCIPAL RESULT: A T-cell count of 560 cells/uL or below signified a trend towards advanced disease | ||
| 520 | |a KEY FINDINGS AND CONCLUSIONS: | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Index Severity Score of infection | |
| 650 | 4 | |a Influenza virus | |
| 650 | 4 | |a SARS-CoV disease | |
| 650 | 4 | |a T-cell apoptosis and sequestration | |
| 650 | 4 | |a T-cell differential counts | |
| 650 | 4 | |a T-cell lymphocytopenia | |
| 700 | 1 | |a Seghatchian, Jerard |e verfasserin |4 aut | |
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