Clinical outcomes of handmade polytetrafluoroethylene trileaflet-valved conduit used for pulmonary valve replacement

© The Author(s) 2023. Published by Oxford University Press on behalf of the European Association for Cardio-Thoracic Surgery. All rights reserved..

OBJECTIVES: To mitigate the shortage of homograft sources, the use of handmade trileaflet expanded polytetrafluoroethylene valves in pulmonary valve replacement has shown excellent results from multicentre studies conducted in Japan. However, world-wide data outside Japan are relatively insufficient. This study presents the long-term results of a single surgeon's use of flipped-back trileaflet method in a 10-year case series.

METHODS: We have developed an efficient way to make a trileaflet-valved conduit utilizing flipped-back method for pulmonary valve replacement and have employed the technique since 2011. Retrospective data were studied between October 2010 and January 2020. Echocardiography, electrocardiogram, Pro-Brain Natriuretic Peptide and Magnetic Resonance Imaging data were analysed.

RESULTS: Fifty-five patients were reviewed and median follow-up duration was 2.9 years. The majority of diagnoses was Tetralogy of Fallot (n = 41), and these patients subsequently underwent secondary pulmonary valve replacement at a median age of 15.6 years. Survival was 92.7% with the longest follow-up period being 10 years. There was no need for reoperation, and freedom from reintervention was 98.0% at 10 years. There were 4 deaths (3 in-hospital and 1 outpatient). One patient eventually received transcatheter pulmonary valve implantation. Postoperative echocardiography showed mild or less pulmonary stenosis and pulmonary regurgitation degree in 92.2% and 92.0% of patients, respectively. Comparable magnetic resonance imaging data (n = 25) showed significant reduction in right ventricular volumes but not in ejection fractions.

CONCLUSIONS: Our series showed satisfactory long-term function of handmade flipped-back trileaflet-valved conduit used in our patients. The simple design is efficiently reproducible without complex fabrication process.

Medienart:

E-Artikel

Erscheinungsjahr:

2023

Erschienen:

2023

Enthalten in:

Zur Gesamtaufnahme - volume:63

Enthalten in:

European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery - 63(2023), 6 vom: 01. Juni

Sprache:

Englisch

Beteiligte Personen:

Chang, Te-I [VerfasserIn]
Hsu, Kang-Hong [VerfasserIn]
Hung, Wei-Li [VerfasserIn]
Yeh, Shu-Jen [VerfasserIn]
Chen, Ming-Ren [VerfasserIn]
Chien, Yu-San [VerfasserIn]
Hsu, Ron-Bin [VerfasserIn]
Wang, Jou-Kou [VerfasserIn]
Chang, Ruey-Feng [VerfasserIn]
Chang, Chung-I [VerfasserIn]

Links:

Volltext

Themen:

9002-84-0
Journal Article
Polytetrafluoroethylene
Polytetrafluoroethylene valve
Pulmonary valve replacement
Right ventricular outflow tract reconstruction
Tetralogy of Fallot

Anmerkungen:

Date Completed 03.07.2023

Date Revised 06.12.2023

published: Print

Citation Status MEDLINE

doi:

10.1093/ejcts/ezad120

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM354766570