The effect of diabetes on COVID-19 incidence and mortality : Differences between highly-developed-country and high-migratory-pressure-country populations
Copyright © 2023 Ottone, Bartolini, Bonvicini, Giorgi Rossi and Reggio Emilia COVID-19 working group..
The objective of this study was to compare the effect of diabetes and pathologies potentially related to diabetes on the risk of infection and death from COVID-19 among people from Highly-Developed-Country (HDC), including Italians, and immigrants from the High-Migratory-Pressure-Countries (HMPC). Among the population with diabetes, whose prevalence is known to be higher among immigrants, we compared the effect of body mass index among HDC and HMPC populations. A population-based cohort study was conducted, using population registries and routinely collected surveillance data. The population was stratified into HDC and HMPC, according to the place of birth; moreover, a focus was set on the South Asiatic population. Analyses restricted to the population with type-2 diabetes were performed. We reported incidence (IRR) and mortality rate ratios (MRR) and hazard ratios (HR) with 95% confidence interval (CI) to estimate the effect of diabetes on SARS-CoV-2 infection and COVID-19 mortality. Overall, IRR of infection and MRR from COVID-19 comparing HMPC with HDC group were 0.84 (95% CI 0.82-0.87) and 0.67 (95% CI 0.46-0.99), respectively. The effect of diabetes on the risk of infection and death from COVID-19 was slightly higher in the HMPC population than in the HDC population (HRs for infection: 1.37 95% CI 1.22-1.53 vs. 1.20 95% CI 1.14-1.25; HRs for mortality: 3.96 95% CI 1.82-8.60 vs. 1.71 95% CI 1.50-1.95, respectively). No substantial difference in the strength of the association was observed between obesity or other comorbidities and SARS-CoV-2 infection. Similarly for COVID-19 mortality, HRs for obesity (HRs: 18.92 95% CI 4.48-79.87 vs. 3.91 95% CI 2.69-5.69) were larger in HMPC than in the HDC population, but differences could be due to chance. Among the population with diabetes, the HMPC group showed similar incidence (IRR: 0.99 95% CI: 0.88-1.12) and mortality (MRR: 0.89 95% CI: 0.49-1.61) to that of HDC individuals. The effect of obesity on incidence was similar in both HDC and HMPC populations (HRs: 1.73 95% CI 1.41-2.11 among HDC vs. 1.41 95% CI 0.63-3.17 among HMPC), although the estimates were very imprecise. Despite a higher prevalence of diabetes and a stronger effect of diabetes on COVID-19 mortality in HMPC than in the HDC population, our cohort did not show an overall excess risk of COVID-19 mortality in immigrants.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2023 |
|---|---|
| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:11 |
|---|---|
| Enthalten in: |
Frontiers in public health - 11(2023) vom: 15., Seite 969143 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Ottone, Marta [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
COVID-19 mortality |
|---|
| Anmerkungen: |
Date Completed 28.03.2023 Date Revised 28.03.2023 published: Electronic-eCollection Citation Status MEDLINE |
|---|
| doi: |
10.3389/fpubh.2023.969143 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM354746871 |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM354746871 | ||
| 003 | DE-627 | ||
| 005 | 20231226062859.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231226s2023 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.3389/fpubh.2023.969143 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1182.xml |
| 035 | |a (DE-627)NLM354746871 | ||
| 035 | |a (NLM)36969620 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Ottone, Marta |e verfasserin |4 aut | |
| 245 | 1 | 4 | |a The effect of diabetes on COVID-19 incidence and mortality |b Differences between highly-developed-country and high-migratory-pressure-country populations |
| 264 | 1 | |c 2023 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 28.03.2023 | ||
| 500 | |a Date Revised 28.03.2023 | ||
| 500 | |a published: Electronic-eCollection | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright © 2023 Ottone, Bartolini, Bonvicini, Giorgi Rossi and Reggio Emilia COVID-19 working group. | ||
| 520 | |a The objective of this study was to compare the effect of diabetes and pathologies potentially related to diabetes on the risk of infection and death from COVID-19 among people from Highly-Developed-Country (HDC), including Italians, and immigrants from the High-Migratory-Pressure-Countries (HMPC). Among the population with diabetes, whose prevalence is known to be higher among immigrants, we compared the effect of body mass index among HDC and HMPC populations. A population-based cohort study was conducted, using population registries and routinely collected surveillance data. The population was stratified into HDC and HMPC, according to the place of birth; moreover, a focus was set on the South Asiatic population. Analyses restricted to the population with type-2 diabetes were performed. We reported incidence (IRR) and mortality rate ratios (MRR) and hazard ratios (HR) with 95% confidence interval (CI) to estimate the effect of diabetes on SARS-CoV-2 infection and COVID-19 mortality. Overall, IRR of infection and MRR from COVID-19 comparing HMPC with HDC group were 0.84 (95% CI 0.82-0.87) and 0.67 (95% CI 0.46-0.99), respectively. The effect of diabetes on the risk of infection and death from COVID-19 was slightly higher in the HMPC population than in the HDC population (HRs for infection: 1.37 95% CI 1.22-1.53 vs. 1.20 95% CI 1.14-1.25; HRs for mortality: 3.96 95% CI 1.82-8.60 vs. 1.71 95% CI 1.50-1.95, respectively). No substantial difference in the strength of the association was observed between obesity or other comorbidities and SARS-CoV-2 infection. Similarly for COVID-19 mortality, HRs for obesity (HRs: 18.92 95% CI 4.48-79.87 vs. 3.91 95% CI 2.69-5.69) were larger in HMPC than in the HDC population, but differences could be due to chance. Among the population with diabetes, the HMPC group showed similar incidence (IRR: 0.99 95% CI: 0.88-1.12) and mortality (MRR: 0.89 95% CI: 0.49-1.61) to that of HDC individuals. The effect of obesity on incidence was similar in both HDC and HMPC populations (HRs: 1.73 95% CI 1.41-2.11 among HDC vs. 1.41 95% CI 0.63-3.17 among HMPC), although the estimates were very imprecise. Despite a higher prevalence of diabetes and a stronger effect of diabetes on COVID-19 mortality in HMPC than in the HDC population, our cohort did not show an overall excess risk of COVID-19 mortality in immigrants | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Research Support, Non-U.S. Gov't | |
| 650 | 4 | |a COVID-19 mortality | |
| 650 | 4 | |a SARS-CoV-2 infection | |
| 650 | 4 | |a diabetes register | |
| 650 | 4 | |a immigrants | |
| 650 | 4 | |a type-2 diabetes | |
| 700 | 1 | |a Bartolini, Letizia |e verfasserin |4 aut | |
| 700 | 1 | |a Bonvicini, Laura |e verfasserin |4 aut | |
| 700 | 1 | |a Giorgi Rossi, Paolo |e verfasserin |4 aut | |
| 700 | 0 | |a Reggio Emilia COVID-19 working group |e verfasserin |4 aut | |
| 700 | 1 | |a Costantini, Massimo |e investigator |4 oth | |
| 700 | 1 | |a Grilli, Roberto |e investigator |4 oth | |
| 700 | 1 | |a Marino, Massimiliano |e investigator |4 oth | |
| 700 | 1 | |a Formoso, Giulio |e investigator |4 oth | |
| 700 | 1 | |a Formisano, Debora |e investigator |4 oth | |
| 700 | 1 | |a Venturi, Ivano |e investigator |4 oth | |
| 700 | 1 | |a Campari, Cinzia |e investigator |4 oth | |
| 700 | 1 | |a Gioia, Francesco |e investigator |4 oth | |
| 700 | 1 | |a Broccoli, Serena |e investigator |4 oth | |
| 700 | 1 | |a Ottone, Marta |e investigator |4 oth | |
| 700 | 1 | |a Pattacini, Pierpaolo |e investigator |4 oth | |
| 700 | 1 | |a Besutti, Giulia |e investigator |4 oth | |
| 700 | 1 | |a Iotti, Valentina |e investigator |4 oth | |
| 700 | 1 | |a Spaggiari, Lucia |e investigator |4 oth | |
| 700 | 1 | |a Seidenari, Chiara |e investigator |4 oth | |
| 700 | 1 | |a Veronesi, Licia |e investigator |4 oth | |
| 700 | 1 | |a Affanni, Paola |e investigator |4 oth | |
| 700 | 1 | |a Colucci, Maria Eugenia |e investigator |4 oth | |
| 700 | 1 | |a Nitrosi, Andrea |e investigator |4 oth | |
| 700 | 1 | |a Foracchia, Marco |e investigator |4 oth | |
| 700 | 1 | |a Colla, Rossana |e investigator |4 oth | |
| 700 | 1 | |a Massari, Marco |e investigator |4 oth | |
| 700 | 1 | |a Ferrari, Anna Maria |e investigator |4 oth | |
| 700 | 1 | |a Pinotti, Mirco |e investigator |4 oth | |
| 700 | 1 | |a Facciolongo, Nicola |e investigator |4 oth | |
| 700 | 1 | |a Lattuada, Ivana |e investigator |4 oth | |
| 700 | 1 | |a Trabucco, Laura |e investigator |4 oth | |
| 700 | 1 | |a Pietri, Stefano De |e investigator |4 oth | |
| 700 | 1 | |a Danelli, Giorgio Francesco |e investigator |4 oth | |
| 700 | 1 | |a Albertazzi, Laura |e investigator |4 oth | |
| 700 | 1 | |a Bellesia, Enrica |e investigator |4 oth | |
| 700 | 1 | |a Canovi, Simone |e investigator |4 oth | |
| 700 | 1 | |a Corradini, Mattia |e investigator |4 oth | |
| 700 | 1 | |a Fasano, Tommaso |e investigator |4 oth | |
| 700 | 1 | |a Magnani, Elena |e investigator |4 oth | |
| 700 | 1 | |a Pilia, Annalisa |e investigator |4 oth | |
| 700 | 1 | |a Polese, Alessandra |e investigator |4 oth | |
| 700 | 1 | |a Incerti, Silvia Storchi |e investigator |4 oth | |
| 700 | 1 | |a Zaldini, Piera |e investigator |4 oth | |
| 700 | 1 | |a Bonelli, Efrem |e investigator |4 oth | |
| 700 | 1 | |a Orsola, Bonanno |e investigator |4 oth | |
| 700 | 1 | |a Revelli, Matteo |e investigator |4 oth | |
| 700 | 1 | |a Salvarani, Carlo |e investigator |4 oth | |
| 700 | 1 | |a Pinto, Carmine |e investigator |4 oth | |
| 700 | 1 | |a Mancuso, Pamela |e investigator |4 oth | |
| 700 | 1 | |a Venturelli, Francesco |e investigator |4 oth | |
| 700 | 1 | |a Vicentini, Massimo |e investigator |4 oth | |
| 700 | 1 | |a Perilli, Cinzia |e investigator |4 oth | |
| 700 | 1 | |a Larosa, Elisabetta |e investigator |4 oth | |
| 700 | 1 | |a Bisaccia, Eufemia |e investigator |4 oth | |
| 700 | 1 | |a Bedeschi, Emanuela |e investigator |4 oth | |
| 700 | 1 | |a Zerbini, Alessandro |e investigator |4 oth | |
| 700 | 1 | |a Rossi, Paolo Giorgi |e investigator |4 oth | |
| 773 | 0 | 8 | |i Enthalten in |t Frontiers in public health |d 2013 |g 11(2023) vom: 15., Seite 969143 |w (DE-627)NLM23377548X |x 2296-2565 |7 nnns |
| 773 | 1 | 8 | |g volume:11 |g year:2023 |g day:15 |g pages:969143 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.3389/fpubh.2023.969143 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 11 |j 2023 |b 15 |h 969143 | ||