Significance of Vitamin Supplementation in Reducing the Severity of COVID-19

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Coronavirus disease-19 (COVID-19), a serious pandemic due to the SARS-CoV-2 virus infection, caused significant lockdowns, healthcare shortages, and deaths worldwide. The infection leads to an uncontrolled systemic inflammatory response causing severe respiratory distress and multiple-organ failure. Quick development of several vaccines efficiently controlled the spread of COVID-19. However, the rise of various new subvariants of COVID-19 demonstrated some concerns over the efficacy of existing vaccines. Currently, better vaccines to control these variants are still under development as several new subvariants of COVID-19, such as omicron BA-4, BA-5, and BF-7 are still impacting the world. Few antiviral treatments have been shown to control COVID-19 symptoms. Further, control of COVID-19 symptoms has been explored with many natural and synthetic adjuvant compounds in hopes of treating the deadly and contagious disease. Vitamins have been shown to modulate the immune system, function as antioxidants, and reduce the inflammatory response. Recent studies have investigated the potential role of vitamins, specifically vitamins A, B, C, D, and E, in reducing the immune and inflammatory responses and severity of the complication. In this brief article, we discussed our current understanding of the role of vitamins in controlling COVID-19 symptoms and their potential use as adjuvant therapy.

Medienart:

E-Artikel

Erscheinungsjahr:

2024

Erschienen:

2024

Enthalten in:

Zur Gesamtaufnahme - volume:24

Enthalten in:

Mini reviews in medicinal chemistry - 24(2024), 3 vom: 26., Seite 254-264

Sprache:

Englisch

Beteiligte Personen:

Aiges, Myia [VerfasserIn]
Ramana, Kota V [VerfasserIn]

Links:

Volltext

Themen:

11103-57-4
12001-79-5
Adjuvant therapy
COVID-19
Immunity
Inflammation
Journal Article
Severe respiratory distress.
Vaccines
Vitamin A
Vitamin K
Vitamins

Anmerkungen:

Date Completed 30.01.2024

Date Revised 30.01.2024

published: Print

Citation Status MEDLINE

doi:

10.2174/1389557523666230324081713

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM35472522X