The impact of the COVID-19 pandemic on SLE

© Japan College of Rheumatology 2023. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissionsoup.com..

Little is known about the association between coronavirus disease 2019 (COVID-19) and autoimmune diseases, especially in the case of systemic lupus erythematosus (SLE). SLE patients met with many questions during the pandemic in COVID-19, such as how to minimize risk of infection, the complex pathological features and cytokine profiles, diagnosis and treatment, rational choice of drugs and vaccine, good nursing, psychological supervision, and so on. In this study, we review and discuss the multifaceted effects of the COVID-19 pandemic on patients living with SLE using the available literature. Cross-talk in implicated inflammatory pathways/mechanisms exists between SLE and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, and SARS-CoV-2 displays similar clinical characteristics and immuno-inflammatory responses to SLE. Current epidemiological data inadequately assess the risk and severity of COVID-19 infection in patients with SLE. More evidence has shown that hydroxychloroquine and chloroquine cannot prevent COVID-19. During the pandemic, patients with SLE had a higher rate of hospitalization. Vaccination helps to reduce the risk of infection. Several therapies for patients with SLE infected with COVID-19 are discussed. The cases in the study can provide meaningful information for clinical diagnosis and management. Our main aim is to help preventing infection and highlight treatment options for patients with SLE infected with COVID-19.

Medienart:

E-Artikel

Erscheinungsjahr:

2024

Erschienen:

2024

Enthalten in:

Zur Gesamtaufnahme - volume:34

Enthalten in:

Modern rheumatology - 34(2024), 2 vom: 26. Feb., Seite 247-264

Sprache:

Englisch

Beteiligte Personen:

Zhao, Xingwang [VerfasserIn]
Wu, Haohao [VerfasserIn]
Li, Shifei [VerfasserIn]
Gao, Cuie [VerfasserIn]
Wang, Juan [VerfasserIn]
Ge, Lan [VerfasserIn]
Song, Zhiqiang [VerfasserIn]
Ni, Bing [VerfasserIn]
You, Yi [VerfasserIn]

Links:

Volltext

Themen:

4QWG6N8QKH
Autoimmunity
Coronavirus disease 2019
Hydroxychloroquine
Infection
Journal Article
Review
Severe acute respiratory syndrome coronavirus 2
Systemic lupus erythematosus

Anmerkungen:

Date Completed 28.02.2024

Date Revised 28.02.2024

published: Print

Citation Status MEDLINE

doi:

10.1093/mr/road030

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM354668722