Influence of partially exposed nonabsorbable membrane for alveolar ridge preservation : A randomized controlled trial
© 2023 Wiley Periodicals LLC..
AIM: This randomized controlled trial evaluated the impact of a partially exposed non-absorbable membrane (dPTFE) in Alveolar Ridge Preservation (ARP) procedures on clinical, tomographic, immunoenzymatic, implant-related, and patient-centered outcomes.
MATERIALS AND METHODS: Patients with a hopeless maxillary single-rooted tooth demanding rehabilitation with implants were included. Patients were randomized into two groups: dPTFE (n = 22)-tooth extraction followed by ARP using a partially exposed dPTFE membrane; USH (n = 22)-unassisted socket healing. Clinical and tomographic analyses were performed at baseline and after 3 months. After 3 months, patients received one dental implant. Implant stability quotient was obtained following implant placement. Bone-related markers were analyzed in bone biopsies using an immunoenzymatic assay.
RESULTS: Greater gain in Keratinized Mucosa Width (KMW) was observed in the dPTFE (1.33 ± 0.98 mm) compared to USH (0.59 ± 0.98 mm) (Mann-Whitney test, Z = 2,28, p < 0.05). USH showed a reduction of pain/discomfort, edema, and interference with daily life from the seventh day (Friedman/Wilcoxon test, maxT = 7.48, 8.00, and 5.92, respectively, p < 0.05). dPTFE presents a reduction of edema and interference with daily life from the 7th day and pain/discomfort from the 14th day (Friedman/Wilcoxon test, maxT = 5.40, 5.26, and 4.78, respectively, p < 0.05). The dPTFE group presented higher pain/discomfort in the 35 and 42 days and higher edema from 7 to 42 days postoperatively than USH group (Mann-Whitney test, p < 0.05). No differences between groups were observed in the tomographic measures, immunoenzymatic analysis, and implant stability (p > 0.05).
CONCLUSION: dPTFE was superior to USH by increasing KMW gain. However, dPTFE without bone graft presented similar bone loss compared to USH. This clinical trial was not registered prior to participant recruitment and randomization (NCT04329351).
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:25 |
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| Enthalten in: |
Clinical implant dentistry and related research - 25(2023), 3 vom: 22. Juni, Seite 447-457 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Matumoto, Edson Ken [VerfasserIn] |
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| Links: |
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| Themen: |
Alveolar bone loss |
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| Anmerkungen: |
Date Completed 06.06.2023 Date Revised 06.06.2023 published: Print-Electronic ClinicalTrials.gov: NCT04329351 Citation Status MEDLINE |
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| doi: |
10.1111/cid.13202 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM354516124 |
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| 100 | 1 | |a Matumoto, Edson Ken |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Influence of partially exposed nonabsorbable membrane for alveolar ridge preservation |b A randomized controlled trial |
| 264 | 1 | |c 2023 | |
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| 500 | |a Date Completed 06.06.2023 | ||
| 500 | |a Date Revised 06.06.2023 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a ClinicalTrials.gov: NCT04329351 | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a © 2023 Wiley Periodicals LLC. | ||
| 520 | |a AIM: This randomized controlled trial evaluated the impact of a partially exposed non-absorbable membrane (dPTFE) in Alveolar Ridge Preservation (ARP) procedures on clinical, tomographic, immunoenzymatic, implant-related, and patient-centered outcomes | ||
| 520 | |a MATERIALS AND METHODS: Patients with a hopeless maxillary single-rooted tooth demanding rehabilitation with implants were included. Patients were randomized into two groups: dPTFE (n = 22)-tooth extraction followed by ARP using a partially exposed dPTFE membrane; USH (n = 22)-unassisted socket healing. Clinical and tomographic analyses were performed at baseline and after 3 months. After 3 months, patients received one dental implant. Implant stability quotient was obtained following implant placement. Bone-related markers were analyzed in bone biopsies using an immunoenzymatic assay | ||
| 520 | |a RESULTS: Greater gain in Keratinized Mucosa Width (KMW) was observed in the dPTFE (1.33 ± 0.98 mm) compared to USH (0.59 ± 0.98 mm) (Mann-Whitney test, Z = 2,28, p < 0.05). USH showed a reduction of pain/discomfort, edema, and interference with daily life from the seventh day (Friedman/Wilcoxon test, maxT = 7.48, 8.00, and 5.92, respectively, p < 0.05). dPTFE presents a reduction of edema and interference with daily life from the 7th day and pain/discomfort from the 14th day (Friedman/Wilcoxon test, maxT = 5.40, 5.26, and 4.78, respectively, p < 0.05). The dPTFE group presented higher pain/discomfort in the 35 and 42 days and higher edema from 7 to 42 days postoperatively than USH group (Mann-Whitney test, p < 0.05). No differences between groups were observed in the tomographic measures, immunoenzymatic analysis, and implant stability (p > 0.05) | ||
| 520 | |a CONCLUSION: dPTFE was superior to USH by increasing KMW gain. However, dPTFE without bone graft presented similar bone loss compared to USH. This clinical trial was not registered prior to participant recruitment and randomization (NCT04329351) | ||
| 650 | 4 | |a Randomized Controlled Trial | |
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a alveolar bone loss | |
| 650 | 4 | |a biomarkers | |
| 650 | 4 | |a bone regeneration | |
| 650 | 4 | |a clinical study | |
| 650 | 4 | |a dental implants | |
| 650 | 4 | |a radiography | |
| 650 | 4 | |a tooth loss | |
| 700 | 1 | |a Corrêa, Mônica Grazieli |e verfasserin |4 aut | |
| 700 | 1 | |a Couso-Queiruga, Emilio |e verfasserin |4 aut | |
| 700 | 1 | |a Monteiro, Mabelle Freitas |e verfasserin |4 aut | |
| 700 | 1 | |a Graham, Zachary |e verfasserin |4 aut | |
| 700 | 1 | |a Braz, Silvia Helena Garcia |e verfasserin |4 aut | |
| 700 | 1 | |a Ribeiro, Fernanda Vieira |e verfasserin |4 aut | |
| 700 | 1 | |a Pimentel, Suzana Peres |e verfasserin |4 aut | |
| 700 | 1 | |a Cirano, Fabiano Ribeiro |e verfasserin |4 aut | |
| 700 | 1 | |a Casati, Marcio Zaffalon |e verfasserin |4 aut | |
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