Association Between Age- and Sex-Specific Body Mass Index Percentile and Multiple Intubation Attempts : A Retrospective Cohort Analysis

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BACKGROUND: Obesity distorts airways and slightly complicates intubations in adults, but whether obesity complicates pediatric intubations remains unclear. We, therefore, tested the primary hypothesis that increasing age- and sex-specific body mass index (BMI) percentile is associated with difficult intubation, defined as >1 intubation attempt.

METHODS: We conducted a retrospective analysis of pediatric patients between 2 and 18 years of age who had noncardiac surgery with oral endotracheal intubation. We assessed the association between BMI percentile and difficult intubation, defined as >1 intubation attempt, using a confounder-adjusted multivariable logistic regression model. Secondarily, we assessed whether the main association depended on preoperative substantial airway abnormality status or age group.

RESULTS: A total of 9339 patients were included in the analysis. Median [quartiles] age- and sex-specific BMI percentile was 70 [33, 93], and 492 (5.3%) patients had difficult intubation. There was no apparent association between age- and sex-specific BMI percentile and difficult intubation. The estimated odds ratio (OR) for having difficult intubation for a 10-unit increase in BMI percentile was 0.98 (95% confidence interval [CI], 0.95-1.005) and was consistent across the 3 age groups of early childhood, middle childhood, and early adolescence (interaction P = .53). Patients with preoperative substantial airway abnormalities had lower odds of difficult intubation per 10-unit increase in BMI percentile, with OR (95% CI) of 0.83 (0.70-0.98), P = .01.

CONCLUSIONS: Age- and sex-specific BMI percentile was not associated with difficult intubation in children between 2 and 18 years of age. As in adults, obesity in children does not much complicate intubation.

Medienart:

E-Artikel

Erscheinungsjahr:

2024

Erschienen:

2024

Enthalten in:

Zur Gesamtaufnahme - volume:138

Enthalten in:

Anesthesia and analgesia - 138(2024), 4 vom: 01. Apr., Seite 821-828

Sprache:

Englisch

Beteiligte Personen:

Chhabada, Surendrasingh [VerfasserIn]
Skinner, Chelsea [VerfasserIn]
Kopac, Orkun [VerfasserIn]
Castro, Pilar [VerfasserIn]
Mascha, Edward J [VerfasserIn]
Wang, Dong [VerfasserIn]
Gama de Abreu, Marcelo [VerfasserIn]
Turan, Alparslan [VerfasserIn]
Sessler, Daniel I [VerfasserIn]
Ruetzler, Kurt [VerfasserIn]

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Journal Article

Anmerkungen:

Date Completed 18.03.2024

Date Revised 15.04.2024

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1213/ANE.0000000000006400

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM354263978