Pseudotyped Viruses
© 2023. The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd..
Pseudotyped viruses have been constructed for many viruses. They can mimic the authentic virus and have many advantages compared to authentic viruses. Thus, they have been widely used as a surrogate of authentic virus for viral function analysis, detection of neutralizing antibodies, screening viral entry inhibitors, and others. This chapter reviewed the progress in the field of pseudotyped viruses in general, including the definition and the advantages of pseudotyped viruses, their potential usage, different strategies or vectors used for the construction of pseudotyped viruses, and factors that affect the construction of pseudotyped viruses.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:1407 |
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| Enthalten in: |
Advances in experimental medicine and biology - 1407(2023) vom: 15., Seite 1-27 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Wang, Youchun [VerfasserIn] |
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| Links: |
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| Themen: |
Antibodies, Neutralizing |
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| Anmerkungen: |
Date Completed 20.03.2023 Date Revised 20.03.2023 published: Print Citation Status MEDLINE |
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| doi: |
10.1007/978-981-99-0113-5_1 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| 520 | |a Pseudotyped viruses have been constructed for many viruses. They can mimic the authentic virus and have many advantages compared to authentic viruses. Thus, they have been widely used as a surrogate of authentic virus for viral function analysis, detection of neutralizing antibodies, screening viral entry inhibitors, and others. This chapter reviewed the progress in the field of pseudotyped viruses in general, including the definition and the advantages of pseudotyped viruses, their potential usage, different strategies or vectors used for the construction of pseudotyped viruses, and factors that affect the construction of pseudotyped viruses | ||
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