Hyperferritinemic sepsis secondary to invasive Toxoplasma gondii in a child with untreated HIV
Background: Untreated human immunodeficiency virus (HIV)-immunosuppressed pediatric patients show high morbidity and mortality from opportunistic infections. Limited cases of hyperferritinemic sepsis have been described in patients with toxoplasmosis.
Case report: We describe the case of a 13-year-old female patient with a history of untreated HIV who presented with hyperferritinemic sepsis secondary to Toxoplasma gondii infection and Pneumocystis jirovecci pneumonia. She received ventilatory support, inotropic drugs, treatment for opportunistic germs, and high-dose corticosteroids, but with unfavorable evolution.
Conclusions: The global approach to sepsis with elevated ferritin guides to using of therapies aimed at neutralizing the severe inflammatory response. A timely diagnosis would allow prompt treatment and minimize complications.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - year:2023 |
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| Enthalten in: |
Boletin medico del Hospital Infantil de Mexico - (2023) vom: 14. März |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Domínguez-Rojas, Jesús [VerfasserIn] |
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| Links: |
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| Themen: |
Child |
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| Anmerkungen: |
Date Revised 14.03.2023 published: Print-Electronic Citation Status Publisher |
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| doi: |
10.24875/BMHIM.22000051 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM354233599 |
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| 245 | 1 | 0 | |a Hyperferritinemic sepsis secondary to invasive Toxoplasma gondii in a child with untreated HIV |
| 264 | 1 | |c 2023 | |
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| 500 | |a Date Revised 14.03.2023 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status Publisher | ||
| 520 | |a Background: Untreated human immunodeficiency virus (HIV)-immunosuppressed pediatric patients show high morbidity and mortality from opportunistic infections. Limited cases of hyperferritinemic sepsis have been described in patients with toxoplasmosis | ||
| 520 | |a Case report: We describe the case of a 13-year-old female patient with a history of untreated HIV who presented with hyperferritinemic sepsis secondary to Toxoplasma gondii infection and Pneumocystis jirovecci pneumonia. She received ventilatory support, inotropic drugs, treatment for opportunistic germs, and high-dose corticosteroids, but with unfavorable evolution | ||
| 520 | |a Conclusions: The global approach to sepsis with elevated ferritin guides to using of therapies aimed at neutralizing the severe inflammatory response. A timely diagnosis would allow prompt treatment and minimize complications | ||
| 650 | 4 | |a Journal Article | |
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| 650 | 4 | |a Ferritin | |
| 650 | 4 | |a Hemophagocytic | |
| 650 | 4 | |a Human immunodeficiency virus | |
| 650 | 4 | |a Lymphohistiocytosis | |
| 650 | 4 | |a Sepsis | |
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| 700 | 1 | |a Caqui-Vilca, Patrick |e verfasserin |4 aut | |
| 700 | 1 | |a Cruz-Arpi, Mario |e verfasserin |4 aut | |
| 700 | 1 | |a Martel-Ramírez, Carlos |e verfasserin |4 aut | |
| 700 | 1 | |a Quispe-Chipana, Miguel |e verfasserin |4 aut | |
| 700 | 1 | |a Sánchez-Rodríguez, Abel |e verfasserin |4 aut | |
| 700 | 1 | |a Atamari-Anahui, Noé |e verfasserin |4 aut | |
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