Genetic Expression of CYP2B6 Gene in Phenobarbitone Responder and Non- responder Neonates
Quantitative real-time polymerase chain reaction for identifying CYP2B6 gene expression was done on blood samples of 30 phenobarbitone responder and 30 non-responder neonates with seizures. CYP2B6 was observed to be significantly down regulated among phenobarbitone non-responders as compared to phenobarbitone responders (Mean (SD) DCt 17.97 (1.19) vs 15.40 (1.83); P<0.001).
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:60 |
|---|---|
| Enthalten in: |
Indian pediatrics - 60(2023), 3 vom: 15. März, Seite 235-236 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Yadav, Kritika [VerfasserIn] |
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| Themen: |
Anticonvulsants |
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| Anmerkungen: |
Date Completed 15.03.2023 Date Revised 22.06.2023 published: Print Citation Status MEDLINE |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM354219464 |
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| 520 | |a Quantitative real-time polymerase chain reaction for identifying CYP2B6 gene expression was done on blood samples of 30 phenobarbitone responder and 30 non-responder neonates with seizures. CYP2B6 was observed to be significantly down regulated among phenobarbitone non-responders as compared to phenobarbitone responders (Mean (SD) DCt 17.97 (1.19) vs 15.40 (1.83); P<0.001) | ||
| 650 | 4 | |a Letter | |
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| 700 | 1 | |a Aggarwal, Anju |e verfasserin |4 aut | |
| 700 | 1 | |a Banerjee, Basu Dev |e verfasserin |4 aut | |
| 700 | 1 | |a Kumar, Harendar |e verfasserin |4 aut | |
| 700 | 1 | |a Sharma, Tusha |e verfasserin |4 aut | |
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