The Prevalence of Positive Donor Corneoscleral Rim Culture and its Association with Ocular Infection After Transplantation
Copyright: © 2023 by Beyoglu Eye Training and Research Hospital..
Objectives: The aim of the study was to determine the prevalence of positive corneoscleral donor rim cultures and to report keratitis and endophthalmitis after keratoplasty.
Methods: Eye bank records and medical records of patients who underwent keratoplasty between September 1, 2015, and December 31, 2019, were retrospectively reviewed. Patients who had routine donor-rim culture taken during surgery and followed up for at least 1 year in the post-operative period were included in the study.
Results: A total of 826 keratoplasty procedures were performed. A total of 120 (14.5%) cases had a positive donor corneoscleral rim culture. Positive bacterial cultures were obtained from 108 (13.7%) of the donors. Bacterial keratitis was observed in one patient (0.83% of recipients) who had a positive bacterial culture. Positive fungal cultures were obtained from 12 (1.45%) donors, of whom one (8.33% of recipients) developed fungal keratitis. Endophthalmitis was observed in one patient whose culture result was negative. Both bacterial and fungal culture results were similar in penetrating and lamellar surgical procedures.
Conclusion: Although the donor corneoscleral rims have a high positive culture result, the rate of bacterial keratitis and endophthalmitis is low, the risk of infection is high in patients with a fungal positive donor rim. Closer follow-up of patients with fungal positive donor corneo-scleral rim result and initiation of aggressive antifungal treatment when infection occurs will be beneficial.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:8 |
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| Enthalten in: |
Beyoglu eye journal - 8(2023), 1 vom: 07., Seite 50-54 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Bolac, Ruveyde [VerfasserIn] |
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| Links: |
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| Themen: |
Bacterial keratitis |
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| Anmerkungen: |
Date Revised 14.03.2023 published: Electronic-eCollection Citation Status PubMed-not-MEDLINE |
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| doi: |
10.14744/bej.2023.08931 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM35416824X |
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| 245 | 1 | 4 | |a The Prevalence of Positive Donor Corneoscleral Rim Culture and its Association with Ocular Infection After Transplantation |
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| 500 | |a published: Electronic-eCollection | ||
| 500 | |a Citation Status PubMed-not-MEDLINE | ||
| 520 | |a Copyright: © 2023 by Beyoglu Eye Training and Research Hospital. | ||
| 520 | |a Objectives: The aim of the study was to determine the prevalence of positive corneoscleral donor rim cultures and to report keratitis and endophthalmitis after keratoplasty | ||
| 520 | |a Methods: Eye bank records and medical records of patients who underwent keratoplasty between September 1, 2015, and December 31, 2019, were retrospectively reviewed. Patients who had routine donor-rim culture taken during surgery and followed up for at least 1 year in the post-operative period were included in the study | ||
| 520 | |a Results: A total of 826 keratoplasty procedures were performed. A total of 120 (14.5%) cases had a positive donor corneoscleral rim culture. Positive bacterial cultures were obtained from 108 (13.7%) of the donors. Bacterial keratitis was observed in one patient (0.83% of recipients) who had a positive bacterial culture. Positive fungal cultures were obtained from 12 (1.45%) donors, of whom one (8.33% of recipients) developed fungal keratitis. Endophthalmitis was observed in one patient whose culture result was negative. Both bacterial and fungal culture results were similar in penetrating and lamellar surgical procedures | ||
| 520 | |a Conclusion: Although the donor corneoscleral rims have a high positive culture result, the rate of bacterial keratitis and endophthalmitis is low, the risk of infection is high in patients with a fungal positive donor rim. Closer follow-up of patients with fungal positive donor corneo-scleral rim result and initiation of aggressive antifungal treatment when infection occurs will be beneficial | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Bacterial keratitis | |
| 650 | 4 | |a Endophthalmitis | |
| 650 | 4 | |a fungal keratitis | |
| 650 | 4 | |a keratoplasty | |
| 650 | 4 | |a positive donor rim culture | |
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| 700 | 1 | |a Yildiz, Elvin |e verfasserin |4 aut | |
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| 700 | 1 | |a Aksaray, Sebahat |e verfasserin |4 aut | |
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