The association of left atrial mechanics with left ventricular morphology in patients with hypertrophic cardiomyopathy : a cardiac magnetic resonance study
© Pol J Radiol 2023..
Purpose: Hypertrophic cardiomyopathy (HCM) is related with structural and pathologic changes in the left atrium (LA) and left ventricle (LV). The aim of this study was to explore the association between LA mechanics and LV characteristics in patients with HCM using cardiac magnetic resonance feature tracking (CMR-FT).
Material and methods: A total of 76 patients with HCM and 26 healthy controls were included in the study. The parameters including the extent of LV late gadolinium enhancement (LGE-%) and the LV early diastolic longitudinal strain rate (edLSR) were assessed for LV. LA conduit, booster, and reservoir functions were assessed by LA fractional volumes and strain analyses using CMR-FT. HCM patients were classified as HCM patients without LGE, with mild LGE-% (0% < LGE-% ł 10%), and prominent LGE-% (10% < LGE-%).
Results: HCM patients had worse LA functions compared with the controls (p < 0.05). The majority of LA functional indices were more impaired in HCM patients with regard to LGE. LA volumes were higher in HCM patients with prominent LGE-% compared with HCM patients with mild LGE-% (p < 0.05). However, only a minority of LA functional parameters differed between the 2 groups. LA strain parameters showed weak to modest correlations with LV LGE-% and LV edLSR.
Conclusions: LV characteristics, to some extent, influence LA mechanics, but they might not be the only factor inducing LA dysfunction in patients with HCM.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:88 |
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| Enthalten in: |
Polish journal of radiology - 88(2023) vom: 24., Seite e103-e112 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Guler, Arda [VerfasserIn] |
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| Links: |
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| Themen: |
Cardiac magnetic resonance |
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| Anmerkungen: |
Date Revised 14.03.2023 published: Electronic-eCollection Citation Status PubMed-not-MEDLINE |
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| doi: |
10.5114/pjr.2023.125213 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM354164872 |
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| 100 | 1 | |a Guler, Arda |e verfasserin |4 aut | |
| 245 | 1 | 4 | |a The association of left atrial mechanics with left ventricular morphology in patients with hypertrophic cardiomyopathy |b a cardiac magnetic resonance study |
| 264 | 1 | |c 2023 | |
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| 500 | |a Date Revised 14.03.2023 | ||
| 500 | |a published: Electronic-eCollection | ||
| 500 | |a Citation Status PubMed-not-MEDLINE | ||
| 520 | |a © Pol J Radiol 2023. | ||
| 520 | |a Purpose: Hypertrophic cardiomyopathy (HCM) is related with structural and pathologic changes in the left atrium (LA) and left ventricle (LV). The aim of this study was to explore the association between LA mechanics and LV characteristics in patients with HCM using cardiac magnetic resonance feature tracking (CMR-FT) | ||
| 520 | |a Material and methods: A total of 76 patients with HCM and 26 healthy controls were included in the study. The parameters including the extent of LV late gadolinium enhancement (LGE-%) and the LV early diastolic longitudinal strain rate (edLSR) were assessed for LV. LA conduit, booster, and reservoir functions were assessed by LA fractional volumes and strain analyses using CMR-FT. HCM patients were classified as HCM patients without LGE, with mild LGE-% (0% < LGE-% ł 10%), and prominent LGE-% (10% < LGE-%) | ||
| 520 | |a Results: HCM patients had worse LA functions compared with the controls (p < 0.05). The majority of LA functional indices were more impaired in HCM patients with regard to LGE. LA volumes were higher in HCM patients with prominent LGE-% compared with HCM patients with mild LGE-% (p < 0.05). However, only a minority of LA functional parameters differed between the 2 groups. LA strain parameters showed weak to modest correlations with LV LGE-% and LV edLSR | ||
| 520 | |a Conclusions: LV characteristics, to some extent, influence LA mechanics, but they might not be the only factor inducing LA dysfunction in patients with HCM | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a cardiac magnetic resonance | |
| 650 | 4 | |a hypertrophic cardiomyopathy | |
| 650 | 4 | |a late gadolinium enhancement | |
| 650 | 4 | |a left atrium | |
| 700 | 1 | |a Topel, Cagdas |e verfasserin |4 aut | |
| 700 | 1 | |a Sahin, Ahmet Anil |e verfasserin |4 aut | |
| 700 | 1 | |a Aydin, Sinem |e verfasserin |4 aut | |
| 700 | 1 | |a Guler, Ekrem |e verfasserin |4 aut | |
| 700 | 1 | |a Sancar, Kadriye Memic |e verfasserin |4 aut | |
| 700 | 1 | |a Cansever, Aysel Turkvatan |e verfasserin |4 aut | |
| 700 | 1 | |a Guler, Gamze Babur |e verfasserin |4 aut | |
| 700 | 1 | |a Erturk, Mehmet |e verfasserin |4 aut | |
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