Outcomes After Revision Total Knee Arthroplasty From a Specific, Now-Recalled Implant System
Copyright © 2023 Elsevier Inc. All rights reserved..
BACKGROUND: A specific total knee arthroplasty (TKA) implant system was recently recalled for high incidence of early polymeric wear and osteolysis. We analyzed the early outcomes of aseptic revision with these implants.
METHODS: We identified 202 aseptic revision TKAs of this implant system performed at a single institution between 2010 and 2020. Revision indications included aseptic loosening (n = 120), instability (n = 55), and polymeric wear/osteolysis (n = 27). Components were revised in 145 cases (72%) and isolated polyethylene insert exchange occurred in 57 cases (28%). Kaplan-Meier and Cox proportional hazards analyses were used to determine survivorship free from all-cause rerevision and rerevision risk factors.
RESULTS: At 2 and 5 years, survivorship free from all-cause rerevision was 89 and 76% in the polyethylene exchange cohort versus 92 and 84% in the component revision cohort (P = .5). At 2 and 5 years, survivorship in revision with components from the same manufacturer was 89 and 80% compared to 95 and 86% in revision with components from a different manufacturer (P = .2). Among re-revisions (n = 30), cones (37%), sleeves (7%), hinge/distal femoral replacement implants were frequently used (13%). Men had increased risk for rerevision (hazard ratio = 2.3, P = .04).
CONCLUSION: In this series of aseptic revision TKAs performed on a now-recalled implant system, survivorship free from rerevision was lower than expected when components from the same manufacturer were utilized, but comparable to contemporary reports when both the components were revised with an alternative implant system. Metaphyseal fixation with cones and sleeves as well as highly constrained implants was frequently utilized at time of rerevision TKA.
LEVEL OF EVIDENCE: Level IV.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:38 |
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| Enthalten in: |
The Journal of arthroplasty - 38(2023), 6S vom: 15. Juni, Seite S290-S296.e1 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Puri, Simarjeet [VerfasserIn] |
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| Links: |
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| Themen: |
9002-88-4 |
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| Anmerkungen: |
Date Completed 23.05.2023 Date Revised 26.05.2023 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1016/j.arth.2023.03.005 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright © 2023 Elsevier Inc. All rights reserved. | ||
| 520 | |a BACKGROUND: A specific total knee arthroplasty (TKA) implant system was recently recalled for high incidence of early polymeric wear and osteolysis. We analyzed the early outcomes of aseptic revision with these implants | ||
| 520 | |a METHODS: We identified 202 aseptic revision TKAs of this implant system performed at a single institution between 2010 and 2020. Revision indications included aseptic loosening (n = 120), instability (n = 55), and polymeric wear/osteolysis (n = 27). Components were revised in 145 cases (72%) and isolated polyethylene insert exchange occurred in 57 cases (28%). Kaplan-Meier and Cox proportional hazards analyses were used to determine survivorship free from all-cause rerevision and rerevision risk factors | ||
| 520 | |a RESULTS: At 2 and 5 years, survivorship free from all-cause rerevision was 89 and 76% in the polyethylene exchange cohort versus 92 and 84% in the component revision cohort (P = .5). At 2 and 5 years, survivorship in revision with components from the same manufacturer was 89 and 80% compared to 95 and 86% in revision with components from a different manufacturer (P = .2). Among re-revisions (n = 30), cones (37%), sleeves (7%), hinge/distal femoral replacement implants were frequently used (13%). Men had increased risk for rerevision (hazard ratio = 2.3, P = .04) | ||
| 520 | |a CONCLUSION: In this series of aseptic revision TKAs performed on a now-recalled implant system, survivorship free from rerevision was lower than expected when components from the same manufacturer were utilized, but comparable to contemporary reports when both the components were revised with an alternative implant system. Metaphyseal fixation with cones and sleeves as well as highly constrained implants was frequently utilized at time of rerevision TKA | ||
| 520 | |a LEVEL OF EVIDENCE: Level IV | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a aseptic revision | |
| 650 | 4 | |a osteolysis | |
| 650 | 4 | |a polymeric wear synovitis | |
| 650 | 4 | |a rerevision TKA | |
| 650 | 4 | |a revision TKA | |
| 650 | 7 | |a Polyethylene |2 NLM | |
| 650 | 7 | |a 9002-88-4 |2 NLM | |
| 700 | 1 | |a Chandi, Sonia |e verfasserin |4 aut | |
| 700 | 1 | |a Chiu, Yu-Fen |e verfasserin |4 aut | |
| 700 | 1 | |a Blevins, Jason L |e verfasserin |4 aut | |
| 700 | 1 | |a Westrich, Geoffrey H |e verfasserin |4 aut | |
| 700 | 1 | |a Figgie, Mark P |e verfasserin |4 aut | |
| 700 | 1 | |a Sculco, Peter K |e verfasserin |4 aut | |
| 700 | 1 | |a Chalmers, Brian P |e verfasserin |4 aut | |
| 700 | 1 | |a Gausden, Elizabeth B |e verfasserin |4 aut | |
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