A Functional Polymorphism in IL-1B Is Associated With Immune Reconstitution Inflammatory Syndrome of Chronic Disseminated Candidiasis

© The Author(s) 2023. Published by Oxford University Press on behalf of Infectious Diseases Society of America..

We investigated single nucleotide polymorphisms (SNPs) possibly involved in immune reconstitution inflammatory syndrome of chronic disseminated candidiasis (IRIS-CDC) through a candidate gene approach and a prospective matched-control study. We found that an SNP located in interleukin-1B at rs1143627 was significantly associated with the risk of developing IRIS-CDC.

Medienart:

E-Artikel

Erscheinungsjahr:

2023

Erschienen:

2023

Enthalten in:

Zur Gesamtaufnahme - volume:10

Enthalten in:

Open forum infectious diseases - 10(2023), 3 vom: 01. März, Seite ofad078

Sprache:

Englisch

Beteiligte Personen:

Rammaert, Blandine [VerfasserIn]
Bochud, Pierre-Yves [VerfasserIn]
Brunel, Anne-Sophie [VerfasserIn]
Wojtowicz, Agnieszka [VerfasserIn]
Candon, Sophie [VerfasserIn]
Gallego Hernanz, Maria Pilar [VerfasserIn]
Lortholary, Olivier [VerfasserIn]

Links:

Volltext

Themen:

Candida spp
Cytokines
Genetic polymorphism
IL-1B
Immune inflammatory reconstitution syndrome
Invasive fungal diseases
Journal Article

Anmerkungen:

Date Revised 08.03.2023

published: Electronic-eCollection

Citation Status PubMed-not-MEDLINE

doi:

10.1093/ofid/ofad078

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM353854409