Analysis of causes of graft loss in 135 kidney transplant recipients
OBJECTIVE: To investigate the causes of graft loss in kidney transplant recipients.
METHODS: We retrospectively analyzed the clinical data of 135 recipients with graft loss after renal transplantation in the Eighth Medical Center of Chinese PLA General Hospital from January 1, 2002 to January 1, 2022.
RESULTS: A total of 135 kidney transplant recipients experienced graft failure. The causes of graft loss included graft rejection (70 cases, 51.8%), death of the recipients with functional graft (37 cases, 27.4%), surgical complications (12 cases, 8.9%), drug toxicity (4 cases, 3.0%), carbapenem-resistant Klebsiella pneumoniae infection (4 cases, 3.0%), polyoma BK virus-related nephropathy (3 cases, 2.2%), primary nonfunctioning kidney (2 cases, 1.5%), recurrence of primary disease (2 cases, 1.5%), and prerenal acute renal failure (1 case, 0.7%).
CONCLUSION: The main cause of graft loss after renal transplantation is graft rejection, and the secondary cause is death of the recipient with functional graft, and other reasons can be rare.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:43 |
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| Enthalten in: |
Nan fang yi ke da xue xue bao = Journal of Southern Medical University - 43(2023), 1 vom: 20. Jan., Seite 133-138 |
| Sprache: |
Chinesisch |
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| Beteiligte Personen: |
Liu, Y [VerfasserIn] |
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| Links: |
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| Themen: |
Allograft loss |
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| Anmerkungen: |
Date Completed 02.03.2023 Date Revised 04.03.2023 published: Print Citation Status MEDLINE |
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| doi: |
10.12122/j.issn.1673-4254.2023.01.19 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM35362229X |
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| 245 | 1 | 0 | |a Analysis of causes of graft loss in 135 kidney transplant recipients |
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| 500 | |a Date Completed 02.03.2023 | ||
| 500 | |a Date Revised 04.03.2023 | ||
| 500 | |a published: Print | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a OBJECTIVE: To investigate the causes of graft loss in kidney transplant recipients | ||
| 520 | |a METHODS: We retrospectively analyzed the clinical data of 135 recipients with graft loss after renal transplantation in the Eighth Medical Center of Chinese PLA General Hospital from January 1, 2002 to January 1, 2022 | ||
| 520 | |a RESULTS: A total of 135 kidney transplant recipients experienced graft failure. The causes of graft loss included graft rejection (70 cases, 51.8%), death of the recipients with functional graft (37 cases, 27.4%), surgical complications (12 cases, 8.9%), drug toxicity (4 cases, 3.0%), carbapenem-resistant Klebsiella pneumoniae infection (4 cases, 3.0%), polyoma BK virus-related nephropathy (3 cases, 2.2%), primary nonfunctioning kidney (2 cases, 1.5%), recurrence of primary disease (2 cases, 1.5%), and prerenal acute renal failure (1 case, 0.7%) | ||
| 520 | |a CONCLUSION: The main cause of graft loss after renal transplantation is graft rejection, and the secondary cause is death of the recipient with functional graft, and other reasons can be rare | ||
| 650 | 4 | |a English Abstract | |
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a allograft loss | |
| 650 | 4 | |a graft rejection | |
| 650 | 4 | |a kidney recipients with functional graft | |
| 650 | 4 | |a kidney transplantation | |
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| 700 | 1 | |a Qian, Y |e verfasserin |4 aut | |
| 700 | 1 | |a Li, C |e verfasserin |4 aut | |
| 700 | 1 | |a Xiao, L |e verfasserin |4 aut | |
| 700 | 1 | |a Zhu, R |e verfasserin |4 aut | |
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