A case of severe leptospirosis with Jarisch-Herxheimer reaction presenting as respiratory failure
Copyright © 2023 Shi, Guo, Hu, Wang, Li, Hu, Li and Xu..
Background: Leptospirosis is a widespread zoonotic disease caused by pathogenic Leptospira spp. The treatment of penicillin or tetracycline can cause a Jarisch-Herxheimer reaction (JHR), which can lead to acute respiratory distress syndrome (ARDS) and multi-organ failure in severe cases. The overall course of evolution and imaging features of a JHR exacerbation of leptospirosis have rarely been reported.
Case presentation: We present a case of leptospirosis complicated by pulmonary alveolar hemorrhage and a Jarisch-Herxheimer reaction (JHR) that required respiratory and vasopressor support. This case demonstrates a well-defined course of evolution of JHR and the imaging features.
Conclusions: Leptospirosis is easily misdiagnosed in some sporadic areas, and JHR complicates its management. Early diagnosis and appropriate treatment can reduce the mortality of severe leptospirosis with JHR.
Medienart: |
E-Artikel |
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Erscheinungsjahr: |
2023 |
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Erschienen: |
2023 |
Enthalten in: |
Zur Gesamtaufnahme - volume:11 |
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Enthalten in: |
Frontiers in public health - 11(2023) vom: 21., Seite 1125306 |
Sprache: |
Englisch |
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Beteiligte Personen: |
Shi, Yunzhen [VerfasserIn] |
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Links: |
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Anmerkungen: |
Date Completed 28.02.2023 Date Revised 29.03.2023 published: Electronic-eCollection Citation Status MEDLINE |
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doi: |
10.3389/fpubh.2023.1125306 |
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funding: |
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Förderinstitution / Projekttitel: |
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PPN (Katalog-ID): |
NLM353509671 |
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520 | |a Copyright © 2023 Shi, Guo, Hu, Wang, Li, Hu, Li and Xu. | ||
520 | |a Background: Leptospirosis is a widespread zoonotic disease caused by pathogenic Leptospira spp. The treatment of penicillin or tetracycline can cause a Jarisch-Herxheimer reaction (JHR), which can lead to acute respiratory distress syndrome (ARDS) and multi-organ failure in severe cases. The overall course of evolution and imaging features of a JHR exacerbation of leptospirosis have rarely been reported | ||
520 | |a Case presentation: We present a case of leptospirosis complicated by pulmonary alveolar hemorrhage and a Jarisch-Herxheimer reaction (JHR) that required respiratory and vasopressor support. This case demonstrates a well-defined course of evolution of JHR and the imaging features | ||
520 | |a Conclusions: Leptospirosis is easily misdiagnosed in some sporadic areas, and JHR complicates its management. Early diagnosis and appropriate treatment can reduce the mortality of severe leptospirosis with JHR | ||
650 | 4 | |a Case Reports | |
650 | 4 | |a Research Support, Non-U.S. Gov't | |
650 | 4 | |a Jarisch-Herxheimer reaction | |
650 | 4 | |a imaging features | |
650 | 4 | |a leptospirosis | |
650 | 4 | |a metagenomic next-generation sequencing | |
650 | 4 | |a pulmonary alveolar hemorrhage | |
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650 | 7 | |a Tetracycline |2 NLM | |
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700 | 1 | |a Hu, Ming |e verfasserin |4 aut | |
700 | 1 | |a Wang, Yuxuan |e verfasserin |4 aut | |
700 | 1 | |a Li, Jingnan |e verfasserin |4 aut | |
700 | 1 | |a Hu, Wenjuan |e verfasserin |4 aut | |
700 | 1 | |a Li, Xiaomeng |e verfasserin |4 aut | |
700 | 1 | |a Xu, Kaijin |e verfasserin |4 aut | |
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