Myocardial infarction or myocarditis? A case report and review of a myocardial adverse event associated with mRNA vaccine

Copyright © 2023 Badaró, Novaes, Andrade, de Araujo Neto, Machado, Barbosa and Soares..

A 23-year-old man started with chest pain 8 h after his first Pfizer-BioNTech COVID-19 vaccination. ECG evaluation showed sinus tachycardia with ST-segment elevation in D1, AVL, V5, and V6, the findings compatible with acute subepicardial myocardial damage. However, cardiac MRI documented myocardial fibrosis, with cardiac late enhancement non-ischemic pattern with diffuse edema. He had no other symptoms to suggest another etiology than the vaccination. The patient was hospitalized and received corticosteroid (prednisolone) daily. Then, 2 weeks after hospitalization, all laboratory parameters and ECG were normal and the patient was discharged from the hospital. The patient had a history of Wolf-Parkinson White that was corrected with ablation when he was 11 years old. This report calls attention to myocardial adverse reaction risk for mRNA COVID-19 vaccines for people with a previous cardiac disease history.

Medienart:

E-Artikel

Erscheinungsjahr:

2023

Erschienen:

2023

Enthalten in:

Zur Gesamtaufnahme - volume:10

Enthalten in:

Frontiers in medicine - 10(2023) vom: 02., Seite 1071239

Sprache:

Englisch

Beteiligte Personen:

Badaró, Roberto [VerfasserIn]
Novaes, Gustavo [VerfasserIn]
Andrade, Ana Cristina [VerfasserIn]
de Araujo Neto, Cesar Augusto [VerfasserIn]
Machado, Bruna Aparecida [VerfasserIn]
Barbosa, Josiane Dantas Viana [VerfasserIn]
Soares, Milena Botelho Pereira [VerfasserIn]

Links:

Volltext

Themen:

Adverse event
COVID-19
Cardiac disease
Cardiotoxicity
Case Reports
MRNA vaccine

Anmerkungen:

Date Revised 24.02.2023

published: Electronic-eCollection

Citation Status PubMed-not-MEDLINE

doi:

10.3389/fmed.2023.1071239

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM353240486