Nanomaterials as a Potential Target for Infectious Parasitic Agents

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Despite the technological advancement in the era of personalized medicine and therapeutics development, infectious parasitic causative agents remain one of the most challenging areas of research and development. The disadvantages of conventional parasitic prevention and control are the emergence of multiple drug resistance as well as the non-specific targeting of intracellular parasites, which results in high dose concentration needs and subsequently intolerable cytotoxicity. Nanotechnology has attracted extensive interest to reduce medication therapy adverse effects including poor bioavailability and drug selectivity. Numerous nanomaterials-based delivery systems have previously been shown in animal models to be effective in the treatment of various parasitic infections. This review discusses a variety of nanomaterials-based antiparasitic procedures and techniques as well as the processes that allow them to be targeted to different parasitic infections. This review focuses on the key prerequisites for creating novel nanotechnology-based carriers as a potential option in parasite management, specifically in the context of human-related pathogenic parasitic agents.

Medienart:

E-Artikel

Erscheinungsjahr:

2023

Erschienen:

2023

Enthalten in:

Zur Gesamtaufnahme - year:2023

Enthalten in:

Current drug delivery - (2023) vom: 23. Feb.

Sprache:

Englisch

Beteiligte Personen:

Alsharedeh, Rawan H [VerfasserIn]
Rezigue, Meriem [VerfasserIn]
Bashatwah, Rasha M [VerfasserIn]
Amawi, Haneen [VerfasserIn]
Aljabali, Alaa A A [VerfasserIn]
Obeid, Mohammad A [VerfasserIn]
Tambuwala, Murtaza M [VerfasserIn]

Links:

Volltext

Themen:

Antimicrobial
Drug Delivery
Infections
Journal Article
Nanomaterials
Nanoparticles
Parasites

Anmerkungen:

Date Revised 16.02.2024

published: Print-Electronic

Citation Status Publisher

doi:

10.2174/1567201820666230223085403

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM353219061