IMMEDIATE VITRECTOMY vs TAP AND INJECT IN EYES WITH ACUTE POSTCATARACT ENDOPHTHALMITIS AND VISUAL ACUITY ≥HM : A Randomized Clinical Trial

PURPOSE: To compare the outcomes of immediate pars plana vitrectomy (PPV) and tap and inject in eyes with postcataract surgery endophthalmitis.

METHODS: Patients presenting with acute postcataract surgery endophthalmitis and visual acuity between ≥ hand movement and <6/18 were randomized to receive either PPV (Group A) or tap and inject (Group B).

RESULTS: There were 26 and 31 eyes in Group A and Group B, respectively. The final mean visual acuity at 6 weeks [0.14 (Snellen equivalent 6/7.5) versus 0.22 (Snellen equivalent 6/9.5) LogMAR in Groups A and B, respectively; P = 0.2] was similar. However, eyes in Group A had significantly greater mean letter gain in vision compared with Group B (66.36 vs. 43.36, P = 0.02), and more eyes in Group A (88%) than in Group B (65%) attained a visual acuity of ≥ 6/18 ( P = 0.06). Eyes in Group B needed more reinterventions including delayed vitrectomy after tap and inject than those in Group A (39% vs. 8%; P = 0.09). On subgroup analysis, the mean visual acuity at the final follow-up was significantly better in the immediate PPV group compared with the delayed PPV group ( P = 0.04).

CONCLUSION: PPV resulted in earlier recovery, lesser interventions, and greater change in visual acuity than tap and inject in eyes with postcataract surgery endophthalmitis presenting with visual acuity of ≥HM.

Medienart:

E-Artikel

Erscheinungsjahr:

2023

Erschienen:

2023

Enthalten in:

Zur Gesamtaufnahme - volume:43

Enthalten in:

Retina (Philadelphia, Pa.) - 43(2023), 6 vom: 01. Juni, Seite 940-946

Sprache:

Englisch

Beteiligte Personen:

Sen, Alok C [VerfasserIn]
Mehta, Sonali M [VerfasserIn]
Sule, Ashita [VerfasserIn]
More, Amruta V [VerfasserIn]
Shetty, Sachin B [VerfasserIn]
Singh, Jayanti [VerfasserIn]
Tripathi, Shubhi [VerfasserIn]
Agrawal, Rupesh [VerfasserIn]
Talwar, Dinesh [VerfasserIn]

Links:

Volltext

Themen:

Anti-Bacterial Agents
Journal Article
Randomized Controlled Trial

Anmerkungen:

Date Completed 19.01.2024

Date Revised 19.01.2024

published: Print

Citation Status MEDLINE

doi:

10.1097/IAE.0000000000003759

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM352979364