Argentine hemorrhagic fever : report of two cases in a non-endemic area

We present the case of a 38-year-old woman with no relevant medical history, resident of the City of Buenos Aires, who was admitted in hospital for presenting fever, retroocular headache, myalgia, arthralgia, and maculopapular pruritic rash on the back of the hands and feet of 6 days of evolution. Laboratory tests revealed lymphopenia, severe thrombocytopenia, and anicteric hepatitis. Her husband had been hospitalized three weeks earlier for a condition of similar characteristics without etiological diagnosis. Subsequently, it evolved with metrorrhagia and axillary petechiae associated with photophobia, drowsiness, and fine tremor of the tongue with normal cerebrospinal fluid, treated with intravenous ceftriaxone 2 g/day for 7 days. Computed tomography of abdomen and pelvis showed a left abdominal wall hematoma. Serological samples were sent to the National Institute of Human Viral Diseases Dr. Julio I. Maiztegui for dengue virus, leptospirosis and hantavirus with non-reactive results, and RT-PCR of Junín virus that was positive. Retrospectively, the spouse was diagnosed by detection of IgG antibodies to Junin virus by ELISA and neutralization tests. Neither of the two cases had a clear epidemiological link. Our aim is to highlight the importance of clinical suspicion outside of endemic areas.

Medienart:

E-Artikel

Erscheinungsjahr:

2023

Erschienen:

2023

Enthalten in:

Zur Gesamtaufnahme - volume:83

Enthalten in:

Medicina - 83(2023), 1 vom: 31., Seite 129-132

Sprache:

Spanisch

Weiterer Titel:

Fiebre Hemorrágica Argentina: comunicación de dos casos en zona no endémica

Beteiligte Personen:

García Gili, Manuel I [VerfasserIn]
Zampetti, Ana [VerfasserIn]
Asencio, Macarena D [VerfasserIn]
Leone, Cinthia S [VerfasserIn]
Gutiérrez, Magalí [VerfasserIn]
Mindlin, Patricia E [VerfasserIn]

Themen:

Argentine hemorrhagic fever
Case Reports
English Abstract
Interhuman transmission
Serum
Vaccine
Virus

Anmerkungen:

Date Completed 14.02.2023

Date Revised 14.02.2023

published: Print

Citation Status MEDLINE

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM352842067