Opportunistic Infections Post-Lung Transplantation : Viral, Fungal, and Mycobacterial
Copyright © 2022 Elsevier Inc. All rights reserved..
Opportunistic infections are a leading cause of lung transplant recipient morbidity and mortality. Risk factors for infection include continuous exposure of the lung allograft to the external environment, high levels of immunosuppression, impaired mucociliary clearance and decreased cough reflex, and impact of the native lung microbiome in single lung transplant recipients. Infection risk is mitigated through careful pretransplant screening of recipients and donors, implementation of antimicrobial prophylaxis strategies, and routine surveillance posttransplant. This review describes common viral, fungal, and mycobacterial infectious after lung transplant and provides recommendations on prevention and treatment.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:44 |
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| Enthalten in: |
Clinics in chest medicine - 44(2023), 1 vom: 11. März, Seite 159-177 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Magda, Gabriela [VerfasserIn] |
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| Links: |
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| Themen: |
Immunocompromised hosts |
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| Anmerkungen: |
Date Completed 14.02.2023 Date Revised 25.02.2023 published: Print Citation Status MEDLINE |
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| doi: |
10.1016/j.ccm.2022.10.012 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| 520 | |a Opportunistic infections are a leading cause of lung transplant recipient morbidity and mortality. Risk factors for infection include continuous exposure of the lung allograft to the external environment, high levels of immunosuppression, impaired mucociliary clearance and decreased cough reflex, and impact of the native lung microbiome in single lung transplant recipients. Infection risk is mitigated through careful pretransplant screening of recipients and donors, implementation of antimicrobial prophylaxis strategies, and routine surveillance posttransplant. This review describes common viral, fungal, and mycobacterial infectious after lung transplant and provides recommendations on prevention and treatment | ||
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