Cytokine levels in maternal and infant blood after COVID-19 vaccination during pregnancy in comparison with unvaccinated controls
Copyright © 2023 Elsevier B.V. All rights reserved..
The objective of this study was to compare maternal and infant cytokine profiles at delivery among those vaccinated against SARS-CoV-2 during pregnancy to unvaccinated controls. Mother-infant dyads were enrolled in this prospective cohort study, and maternal blood and infant and/or cord blood collected. Samples were analyzed utilizing a LEGENDplex 13-plex human anti-viral response cytokine panel. Maternal IP-10 and IFN-λ2/3 were lower in the vaccinated cohort. In the infants, levels were lower for IL-1β, IFN-λ2/3, and GM-CSF, and higher for IFN-λ1 in the vaccinated cohort. Vaccination against SARS-CoV-2 during pregnancy did not lead to elevations in cytokines in mothers or infants.
| Errataetall: |
CommentIn: J Reprod Immunol. 2023 Jun;157:103947. - PMID 37087817 |
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| Medienart: |
E-Artikel |
| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:156 |
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| Enthalten in: |
Journal of reproductive immunology - 156(2023) vom: 01. März, Seite 103821 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Sabharwal, Vishakha [VerfasserIn] |
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| Links: |
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| Themen: |
COVID-19 |
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| Anmerkungen: |
Date Completed 27.03.2023 Date Revised 28.06.2023 published: Print-Electronic CommentIn: J Reprod Immunol. 2023 Jun;157:103947. - PMID 37087817 Citation Status MEDLINE |
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| doi: |
10.1016/j.jri.2023.103821 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
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| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright © 2023 Elsevier B.V. All rights reserved. | ||
| 520 | |a The objective of this study was to compare maternal and infant cytokine profiles at delivery among those vaccinated against SARS-CoV-2 during pregnancy to unvaccinated controls. Mother-infant dyads were enrolled in this prospective cohort study, and maternal blood and infant and/or cord blood collected. Samples were analyzed utilizing a LEGENDplex 13-plex human anti-viral response cytokine panel. Maternal IP-10 and IFN-λ2/3 were lower in the vaccinated cohort. In the infants, levels were lower for IL-1β, IFN-λ2/3, and GM-CSF, and higher for IFN-λ1 in the vaccinated cohort. Vaccination against SARS-CoV-2 during pregnancy did not lead to elevations in cytokines in mothers or infants | ||
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| 700 | 1 | |a Shaik-Dasthagirisaheb, Yazdan |e verfasserin |4 aut | |
| 700 | 1 | |a Hunnewell, Jessica |e verfasserin |4 aut | |
| 700 | 1 | |a Boateng, Jeffery |e verfasserin |4 aut | |
| 700 | 1 | |a Clarke, Katherine |e verfasserin |4 aut | |
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| 700 | 1 | |a Taglauer, Elizabeth |e verfasserin |4 aut | |
| 700 | 1 | |a Wachman, Elisha M |e verfasserin |4 aut | |
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