A combined model based on CT radiomics and clinical variables to predict uric acid calculi which have a good accuracy
© 2023. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature..
The aim of this study was to develop a CT-based radiomics and clinical variable diagnostic model for the preoperative prediction of uric acid calculi. In this retrospective study, 370 patients with urolithiasis who underwent preoperative urinary CT scans were enrolled. The CT images of each patient were manually segmented, and radiomics features were extracted. Sixteen radiomics features were selected by one-way analysis of variance (ANOVA) and least absolute shrinkage and selection operator (LASSO). Logistic regression (LR), random forest (RF) and support vector machine (SVM) were used to model the selected features, and the model with the best performance was selected. Multivariate logistic regression was used to screen out significant clinical variables, and the radiomics features and clinical variables were combined to construct a nomogram model. The area under the receiver operating characteristic (ROC) curve (AUC), etc., were used to evaluate the diagnostic performance of the model. Among the three machine learning models, the LR model had the best performance and good robustness of the dataset. Therefore, the LR model was used to construct the nomogram. The AUCs of the nomogram model in the training set and validation set were 0.878 and 0.867, respectively, which were significantly higher than those of the radiomics model and the clinical feature model. The CT-based radiomics model based has good performance in distinguishing uric acid stones from nonuric acid stones, and the nomogram model has the best diagnostic performance among the three models. This model can provide an effective reference for clinical decision-making.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2023 |
|---|---|
| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:51 |
|---|---|
| Enthalten in: |
Urolithiasis - 51(2023), 1 vom: 06. Feb., Seite 37 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Wang, Zijie [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
268B43MJ25 |
|---|
| Anmerkungen: |
Date Completed 08.02.2023 Date Revised 27.11.2023 published: Electronic Citation Status MEDLINE |
|---|
| doi: |
10.1007/s00240-023-01405-x |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM352552158 |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM352552158 | ||
| 003 | DE-627 | ||
| 005 | 20231226054005.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231226s2023 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1007/s00240-023-01405-x |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1175.xml |
| 035 | |a (DE-627)NLM352552158 | ||
| 035 | |a (NLM)36745218 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Wang, Zijie |e verfasserin |4 aut | |
| 245 | 1 | 2 | |a A combined model based on CT radiomics and clinical variables to predict uric acid calculi which have a good accuracy |
| 264 | 1 | |c 2023 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 08.02.2023 | ||
| 500 | |a Date Revised 27.11.2023 | ||
| 500 | |a published: Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a © 2023. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature. | ||
| 520 | |a The aim of this study was to develop a CT-based radiomics and clinical variable diagnostic model for the preoperative prediction of uric acid calculi. In this retrospective study, 370 patients with urolithiasis who underwent preoperative urinary CT scans were enrolled. The CT images of each patient were manually segmented, and radiomics features were extracted. Sixteen radiomics features were selected by one-way analysis of variance (ANOVA) and least absolute shrinkage and selection operator (LASSO). Logistic regression (LR), random forest (RF) and support vector machine (SVM) were used to model the selected features, and the model with the best performance was selected. Multivariate logistic regression was used to screen out significant clinical variables, and the radiomics features and clinical variables were combined to construct a nomogram model. The area under the receiver operating characteristic (ROC) curve (AUC), etc., were used to evaluate the diagnostic performance of the model. Among the three machine learning models, the LR model had the best performance and good robustness of the dataset. Therefore, the LR model was used to construct the nomogram. The AUCs of the nomogram model in the training set and validation set were 0.878 and 0.867, respectively, which were significantly higher than those of the radiomics model and the clinical feature model. The CT-based radiomics model based has good performance in distinguishing uric acid stones from nonuric acid stones, and the nomogram model has the best diagnostic performance among the three models. This model can provide an effective reference for clinical decision-making | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Radiomics | |
| 650 | 4 | |a Uric acid stones | |
| 650 | 4 | |a Urolithiasis | |
| 650 | 7 | |a Uric Acid |2 NLM | |
| 650 | 7 | |a 268B43MJ25 |2 NLM | |
| 700 | 1 | |a Yang, Guangjie |e verfasserin |4 aut | |
| 700 | 1 | |a Wang, Xinning |e verfasserin |4 aut | |
| 700 | 1 | |a Cao, Yuanchao |e verfasserin |4 aut | |
| 700 | 1 | |a Jiao, Wei |e verfasserin |4 aut | |
| 700 | 1 | |a Niu, Haitao |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Urolithiasis |d 2013 |g 51(2023), 1 vom: 06. Feb., Seite 37 |w (DE-627)NLM225275902 |x 2194-7236 |7 nnns |
| 773 | 1 | 8 | |g volume:51 |g year:2023 |g number:1 |g day:06 |g month:02 |g pages:37 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1007/s00240-023-01405-x |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 51 |j 2023 |e 1 |b 06 |c 02 |h 37 | ||